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Table 3 Proteins involved in protein modification and metabolism

From: The impact of surfactant protein-A on ozone-induced changes in the mouse bronchoalveolar lavage proteome

  

Normalized Volumes

Mean (SD)

WTFA vs WTO3

p ≤ 0.05

Normalized Volumes

Mean (SD)

KOFA vs KOO3

p ≤ 0.05

WTFA vs KOFA

p ≤ 0.05

WTO3 vs KOO3

p ≤ 0.05

  

WTFA

WTO3

 

KOFA

KOO3

   

14-3-3 zeta

3.75

(0.425)

3.56

(0.285)

 

4.21

(0.329)

4.39

(0.552)

  

*

Adipsin (complement factor D)

2.05

(0.337)

2.43

(0.610)

 

2.13

(0.472)

2.34

(0.655)

   

Alpha-1-antitrypsin 1-1 precursor

1.18

(0.191)

1.04

(0.102)

 

1.35

(0.369)

0.94

(0.210)

   

Alpha-1-antitrypsin 1-6 precursor

2.15

(0.230)

2.94

(0.353)

*

2.85

(0.484)

3.47

(0.712)

 

*

 

Antithrombin-III

3.08

(0.589)

4.54

(0.659)

*

3.53

(0.342)

4.78

(0.454)

*

  

Contrapsin

8.72

(0.626)

13.00

(3.512)

.053

10.28

(1.886)

13.47

(2.994)

   

Haptoglobin

12.71

(2.040)

11.21

(0.835)

 

11.47

(0.326)

7.61

(0.764)

*

 

*

Heat shock protein 1, alpha

0.75

(0.092)

0.95

(0.114)

*

0.70

(0.164)

0.95

(0.076)

*

  

Heat shock protein 70

3.93

(0.807)

5.82

(1.173)

*

4.64

(0.556)

7.79

(1.026)

*

 

*

Kininogen1

5.36

(1.723)

6.99

(0.703)

 

5.89

(0.514)

7.65

(0.456)

*

  

Murinoglobulin-1 precursor (MuG1)

0.77

(0.166)

1.07

(0.136)

*

0.88

(0.073)

1.26

(0.131)

*

 

.08

Plasminogen

8.39

(1.194)

7.35

(0.653)

 

8.82

(0.775)

7.70

(2.054)

   

Pregnancy zone protein

0.76

(0.166)

0.83

(0.059)

 

0.94

(0.343)

1.05

(0.080)

  

*

Protein disulfide-isomerase A3 precursor

5.62

(1.658)

4.87

(1.685)

 

4.67

(0.956)

4.64

(0.211)

   

Prothrombin precursor

(EC 3.4.21.5)

1.42

(0.171)

2.01

(0.423)

*

1.56

(0.167)

2.15

(0.301)

*

  

Serine (or cysteine) proteinase inhibitor, clade A, member 1e

5.34

(0.842)

7.41

(0.723)

*

6.10

(0.636)

8.34

(0.800)

*

  

Transitional endoplasmic reticulum ATPase

1.62

(0.230)

2.94

(1.149)

.066

1.92

(0.469)

3.91

(0.527)

*

  

Tyr 3-monooxygenase/trp 5-monooxygenase activation protein

0.87

(0.059)

1.04

(0.092)

*

0.93

(0.133)

1.24

(0.135)

*

 

.054

  1. The proteins assigned to the protein modification and metabolism and chaperone category (PMM) are listed (n = 18). An arrow indicates whether levels of expression are increased (↑) or decreased (↓) in response to ozone. The mean values for the normalized volumes for each named protein are given for WTFA, WTO3, KOFA, and KOO3. The asterisk indicates whether the p-value for the comparisons of WTFA vs. WTO3; KOFA vs. KOO3; WTFA vs. KOFA; and WTO3 vs. KOO3 was ≤ 0.05. Values that were slightly above 0.05 are also given.