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Table 3 Proteins involved in protein modification and metabolism

From: The impact of surfactant protein-A on ozone-induced changes in the mouse bronchoalveolar lavage proteome

   Normalized Volumes
Mean (SD)
WTFA vs WTO3
p ≤ 0.05
Normalized Volumes
Mean (SD)
KOFA vs KOO3
p ≤ 0.05
WTFA vs KOFA
p ≤ 0.05
WTO3 vs KOO3
p ≤ 0.05
   WTFA WTO3   KOFA KOO3    
14-3-3 zeta
3.75
(0.425)
3.56
(0.285)
  4.21
(0.329)
4.39
(0.552)
   *
Adipsin (complement factor D) 2.05
(0.337)
2.43
(0.610)
  2.13
(0.472)
2.34
(0.655)
   
Alpha-1-antitrypsin 1-1 precursor 1.18
(0.191)
1.04
(0.102)
  1.35
(0.369)
0.94
(0.210)
   
Alpha-1-antitrypsin 1-6 precursor 2.15
(0.230)
2.94
(0.353)
* 2.85
(0.484)
3.47
(0.712)
  *  
Antithrombin-III 3.08
(0.589)
4.54
(0.659)
* 3.53
(0.342)
4.78
(0.454)
*   
Contrapsin 8.72
(0.626)
13.00
(3.512)
.053 10.28
(1.886)
13.47
(2.994)
   
Haptoglobin 12.71
(2.040)
11.21
(0.835)
  11.47
(0.326)
7.61
(0.764)
*   *
Heat shock protein 1, alpha 0.75
(0.092)
0.95
(0.114)
* 0.70
(0.164)
0.95
(0.076)
*   
Heat shock protein 70 3.93
(0.807)
5.82
(1.173)
* 4.64
(0.556)
7.79
(1.026)
*   *
Kininogen1 5.36
(1.723)
6.99
(0.703)
  5.89
(0.514)
7.65
(0.456)
*   
Murinoglobulin-1 precursor (MuG1) 0.77
(0.166)
1.07
(0.136)
* 0.88
(0.073)
1.26
(0.131)
*   .08
Plasminogen 8.39
(1.194)
7.35
(0.653)
  8.82
(0.775)
7.70
(2.054)
   
Pregnancy zone protein 0.76
(0.166)
0.83
(0.059)
  0.94
(0.343)
1.05
(0.080)
   *
Protein disulfide-isomerase A3 precursor 5.62
(1.658)
4.87
(1.685)
  4.67
(0.956)
4.64
(0.211)
   
Prothrombin precursor
(EC 3.4.21.5)
1.42
(0.171)
2.01
(0.423)
* 1.56
(0.167)
2.15
(0.301)
*   
Serine (or cysteine) proteinase inhibitor, clade A, member 1e 5.34
(0.842)
7.41
(0.723)
* 6.10
(0.636)
8.34
(0.800)
*   
Transitional endoplasmic reticulum ATPase 1.62
(0.230)
2.94
(1.149)
.066 1.92
(0.469)
3.91
(0.527)
*   
Tyr 3-monooxygenase/trp 5-monooxygenase activation protein 0.87
(0.059)
1.04
(0.092)
* 0.93
(0.133)
1.24
(0.135)
*   .054
  1. The proteins assigned to the protein modification and metabolism and chaperone category (PMM) are listed (n = 18). An arrow indicates whether levels of expression are increased (↑) or decreased (↓) in response to ozone. The mean values for the normalized volumes for each named protein are given for WTFA, WTO3, KOFA, and KOO3. The asterisk indicates whether the p-value for the comparisons of WTFA vs. WTO3; KOFA vs. KOO3; WTFA vs. KOFA; and WTO3 vs. KOO3 was ≤ 0.05. Values that were slightly above 0.05 are also given.