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Figure 3 | Proteome Science

Figure 3

From: Proteins altered by elevated levels of palmitate or glucose implicated in impaired glucose-stimulated insulin secretion

Figure 3

Normalized expression of the 7.14 kDa protein in INS-1E cells by CPT1 over-expressing. The 7.14 kDa protein was elevated in INS-1E cells cultured in the presence of 20 mM glucose and 0.5 mM palmitate. Enhanced CPT1-expression induced by 0.2 or 1 μM doxycycline, normalized the levels of the 7.14 kDa protein. Results are means ± SEM for six independent experiments. *P < 0.05 compared to cells cultured at 20 mM glucose, #p < 0.05 compared to non-induced INS-1E cells cultured in the presence of 20 mM glucose and palmitate.

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ISSN: 1477-5956