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Figure 5 | Proteome Science

Figure 5

From: Proteomic profiling of glucocorticoid-exposed myogenic cells: Time series assessment of protein translocation and transcription of inactive mRNAs

Figure 5

Network analysis of translocated proteins. All proteins (n = 69) showing significant translocation in or out of the cytosol or nuclei following prednisone exposure were loaded into Ingenuity Pathway Analysis. This analysis queries published protein-protein or gene-protein interactions between members of the 69 protein set. Proteins were placed in the subcellular fraction in which they were found to change abundance. Red indicates an increase in that fraction, green a decrease. This network includes a sub-network centered on ANXA2 and is connected with ribosomal proteins and other proteins involved in translational machinery. White color indicates proteins mapped to the network that were part of the imported data. Solid line indicates a direct interaction between molecules. Dashed lines indicate an indirect interaction between molecules.

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