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Figure 2 | Proteome Science

Figure 2

From: Transchromosomic cell model of Down syndrome shows aberrant migration, adhesion and proteome response to extracellular matrix

Figure 2

Cell migration of the WA17 cell line model of DS. (A) A9 and WA17 cells were grown until confluent, and treated with 10 mg/ml mitomycin C for 2 h, before a scratch wound was introduced using a yellow pipette tip. Cells were then incubated for 3 days in normal growth media. Pictures were taken at 0, 1, 2 and 3 days after wounding. (B) Pictures from 4 non-overlapping scratch wounds of each of 3 independent cultures (n = 12 data points for each cell line) from part A were taken and cells migrated into the wound site were quantified (Open bars A9, filled bars WA17). Data are presented as mean ± SD (**p < 0.001 t-test comparing A9 versus WA17).

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