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Table 1 Auxiological data for the study groups

From: Proteins related to lipoprotein profile were identified using a pharmaco-proteomic approach as markers for growth response to growth hormone (GH) treatment in short prepubertal children

A) Total group (n = 128; 38 girls, 90 boys)

B) ISS (n = 89, 25 girls, 64 boys)

C) GHD (n = 39, 13 girls, 26 boys)

Variables

Median

Min

Max

Median

Min

Max

Median

Min

Max

At birth

   Gestational age (weeks)

39

33

42

39

33

42

39

36

42

   Height SDS

-0,66

-2,52

1,68

-0,74

-2,52

1,68

-0,70

-2,52

1,68

At GH start

   Age (yrs)

7,27

3,05

10,95

7,32

3,24

10,95

7,14

3,05

10,94

   Height SDS

-2,64

-4,10

-1,77

-2,64

-4,10

-1,77

-2,59

-3,65

-1,98

   Weight SDS

-2,24

-4,31

0,26

-2,39

-4,31

-0,45

-2,03

-3,80

0,26

   BMI SDS

-0,47

-3,35

2,11

-0,55

-3,35

1,88

-0,20

-1,80

2,11

   GHmax AITT (mU/L)

16,95

1,10

62,90

19,60

1,10

62,90

15,10

1,60

22,30

   GHmax 24 h (mU/L)

24,85

0,80

58,10

28,10

12,70

58,10

14,70

0,80

22,10

   Diff MPHSDS

-1,73

-3,53

-0,61

-1,72

-3,53

-0,61

-1,77

-2,45

-0,78

   HDL (mg/L)

1,44

0,64

2,70

1,44

0,64

2,70

1,44

0,91

2,24

   IGF-I SDS

-1,10

-5,17

2,25

-1,19

-3,84

2,25

-1,06

-5,17

0,91

   GH dose (μg/kg/day)

44,20

17,00

102,00

44,20

17,00

102,00

44,20

17,00

68,00

After 2 yrs of treatment

   Height SDS

-1,45

-3,00

0,20

-1,45

-3,00

0,20

-1,45

-2,42

0,05

   Delta height SDS 2 yrs

1,26

0,23

2,69

1,22

0,23

2,69

1,31

0,51

2,39

   BMI SDS

-0,24

-3,10

2,03

-0,05

-3,10

1,88

-0,08

-2,14

2,03

   HDL (mg/L)

1,36

0,76

2,06

1,37

0,76

2,06

1,28

0,94

1,97

   IGF-I SDS

1,57

-1,48

4,21

1,49

-0,65

3,82

1,57

-1,48

4,21

  1. AITT, arginine--insulin tolerance test; GHmax, maximum peak of GH secretion; IGF-I, insulin-like growth factor I; GHD, GH deficient; MPH, mid-parental height; diffMPHSDS, difference in height SDS of the child versus its mid-parental height SDS
  2. 0.1 U GH/kg/day = 33 μg/kg/day
  3. The reference values used for SDS calculations were obtained from [18] for height and weight and [15] for IGF-I.