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Figure 3 | Proteome Science

Figure 3

From: Downregulated expression of HSP27 in human low-grade glioma tissues discovered by a quantitative proteomic analysis

Figure 3

The representative pairs of isotope labeling peptides to quantify HSP expression in glioma tissues. (A)-(B) was the peak intensity of isotope labeling peptide "SQIHDIV L VGGSTR" of HSPA8(71 KD) respectively from HGTs/H4 (A) and PBTs/H4(B) samples. A: the SILAC ratio1 (HGTs/H4) of HSPA8 was 0.52 ± 0.9; B: the SILAC ratio2 (PBTs/H4) of HSPA8 was 0.55 ± 0.1. The change ratio (HGTs/PBTs) was 0.95 (0.52/0.55) indicated HSPA8 was no significant change between glioma tissues and para-cancerous brain tissues. Similarly, the pairs of isotope labeling peptide " LATQSNEITIPVTFESR" of HSP27(HSPB1) from HGTs/H4 (C) and PBTs/H4(D) samples for quantitation, and the change ratio of 0.48 (0.29/0.61) showed HSP27 was down-regulated in glioma tissues.

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