From: Proteomic analysis of primary duck hepatocytes infected with duck hepatitis B virus
Protein Name | Functions indicated in viral infections | References |
---|---|---|
Aconitase 2, mitochondrial | Binding to the 3'-untranslated region of the mouse hepatitis virus genome and increasing virus production as well as viral protein synthesis at early hours of infection | Nanda et al., 2001. J Virol. 75, 3352-62. |
Phosphoglycerate kinase 1 | Regulating Sendai virus transcription through their interactions with tubulin | Ogino et al., 2001. Biochem Biophys Res Commun. 285, 447-55. |
Triosephosphate isomerase | Increased between cancerous and noncancerous tissues from hepatocellular carcinoma patients | Kuramitsu et al., 2005. Expert Rev Proteomics. 2, 589-601. |
Phosphoglycerate mutase 1 | Specifically binding to the core region of HCV RNA genome in vitro | Su et al., 2007. Intervirology. 50, 303-9. |
Alpha-enolase | A candidate biomarker for HCV-related hepatocellular carcinoma; required for efficient transcription of Sendai virus genome | Takashima et al., 2005. Proteomics. 5, 1686-92. Ogino et al., 2001. Biochem Biophys Res Commun. 285, 447-55. |
GAPDH | May interfere in the life-cycle of HBV to phosphorylate HBV core protein and playing roles in HBV infection in intracellular processes | Duclos-Vallee et al., 1998. J Gen Virol. 79 (Pt 7), 1665-70. Duclos-Vallee et al., 2002. Hepatol Res. 22, 65-73. |
Lamin A | Impeding HSV-1 infectivity; Phosphorylated in HSV-infected cells, regulating virus capsid nuclear egress; Epstein-Barr virus reactivation-mediated redistribution of nuclear lamin to modulate the cellular environment for virion production; cytomegalovirus induced distortion of the nuclear lamina | Mou et al., 2008. J Virol. 82, 8094-104. Mou et al., 2007. J Virol. 81, 6459-70. Lee et al., 2008. J Virol. 82, 11913-26. Milbradt et al., 2007. J Gen Virol. 88, 2642-50. |
Beta-actin | Actin rearrangements contribute to Simian virus 40 endocytosis; required by viral particle up-taking and infection establishment, including HIV, adenovirus, Simian virus 40, and vaccinia virus, etc | Pelkmans et al., 2002. Science. 296, 535-9. Pollard et al., 2003. Cell. 112, 453-65. Bukrinskaya et al., 1998. J Exp Med. 188, 2113-25. Li et al., 1998. J Virol. 72, 8806-12. Ploubidou et al., 2001. Curr Opin Cell Biol. 13, 97-105. |
Dynein, light chain | Regulating Gag and viral RNA egress on endosomal membranes in the cytoplasm to directly impact on viral production; microtubule-dependent dynein activity increased through activation of the p38 MAPK by HBx, perhaps facilitating the process of maturation; directly used by poliovirus for retrograde axonal transport | Lehmann et al., 2009. J Biol Chem. 284, 14572-85. Kim et al., 2007. J Virol. 81, 1714-26. Gonzalez et al., 2007. Intervirology. 50, 214-8. |
Cofilin-2 | Possible involving in the process of HIV initial binding and fusion steps, and inhibiting some subsequent early post-entry events in HIV infection of T cells | Liu et al., 2009. Sci Signal. 2, pe23. |
Heat shock protein 70B | HBV P protein activation in vitro is fundamentally dependent on Hsc70/Hsp40; involving in HBV morphogenesis as a chaperone | Beck et al., 2003. J Biol Chem. 278, 36128-38. Prange et al., 1999. Biol Chem. 380, 305-14. |
Annexin A2 | Assisting in the assembly of HIV, and supporting HIV-1 infection as a cellular cofactor; enhancing cytomegalovirus binding and membrane fusion and supporting the replication of influenza viruses by mediating activation of plasminogen | Ma et al., 2004. J Exp Med. 200, 1337-46. Raynor et al., 1999. Biochemistry. 38, 5089-95. LeBouder et al., 2008. J Virol. 82, 6820-8. |
Elongation factor 2 | Interacting with hepatitis B virus core protein in leukocytes; possessing a highly conserved anti-apoptotic activity induced by HIV-1 viral protein R | Lin et al., 2006. World J Gastroenterol. 12, 1043-8. Zelivianski et al., 2006. Apoptosis. 11, 377-88. |
Ovotransferrin | Playing a crucial role in protecting the whole chicken embryo fibroblasts from Marek's disease virus infection spreading | Giansanti et al., 2007. Biochem Cell Biol. 85, 150-5. |