Quantitative comparison of lipoprotein fractions derived from human plasma and serum by liquid chromatography-tandem mass spectrometry

Table 1 Proteins unique to the LDL fraction.

Protein Accession	Protein Description	Plasma Avg. Scan Count ± SEM	Serum Avg. Scan Count ± SEM
P02745	Complement C1q subcomponent subunit A	1 ± 0.63	1.2 ± 0.63
P02746	Complement C1q subcomponent subunit B	1 ± 0.52	2.2 ± 0.95
P02747	Complement C1q subcomponent subunit C	1.7 ± 0.47	3 ± 1.3
P00736	Complement C1r subcomponent	5.7 ± 1.7	3.2 ± 2.6
P09871	Complement C1 s subcomponent	0.33 ± 0.30	0.8 ± 0.48
P20851	C4b-binding protein beta chain	0.67 ± 0.47	1.4 ± 1.2
O43866	CD5 antigen-like	8.3 ± 2.8	12.8 ± 4.2
P00488	Coagulation factor XIII A chain	0.33 ± 0.30	0
O75636	Ficolin-3	0.17 ± 0.24	1.2 ± 0.48
P07359	Platelet glycoprotein Ib alpha chain	0.17 ± 0.24	0.4 ± 0.5
P69905	Hemoglobin subunit alpha	18.2 ± 25 *	1.8 ± 1.4
P68871	Hemoglobin subunit beta	34.5 ± 48 *	5.6 ± 3
Q08380	Galectin-3-binding protein	2.3 ± 1.3	2.2 ± 1.3
Q93074	Mediator of RNA polymerase II transcription subunit 12	0.33 ± 0.47	2.6 ± 1.9
P27918	Properdin	0	0.8 ± 0.6
P07225	Vitamin K-dependent protein S	2.8 ± 1.9	3.4 ± 3.5

The average scan count ± SEM is provided for each protein identified in only the LDL fraction derived from both plasma and serum. (P < 0.001; * significantly greater in plasma;† significantly greater in serum)

ISSN: 1477-5956