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Table 2 Proteins unique to the HDL fraction.

From: Quantitative comparison of lipoprotein fractions derived from human plasma and serum by liquid chromatography-tandem mass spectrometry

Protein Accession

Protein Description

Plasma Avg. Scan Count ± SEM

Serum Avg. Scan Count ± SEM

P02763

Alpha-1-acid glycoprotein 1

7.3 ± 6.5

5.1 ± 4.7

P19652

Alpha-1-acid glycoprotein 2

2 ± 1.3

0.67 ± 0.41

P04217

Alpha- 1B-glycoprotein

5.1 ± 3.9

5.2 ± 4.3

P08697

Alpha-2-antiplasmin

2.6 ± 1.7

2.6 ± 1.9

P02750

Leucine-rich alpha-2-glycoprotein

0.89 ± 0.79

0.89 ± 1.2

P01011

Alpha-1-antichymotrypsin

6.9 ± 5.4

6.2 ± 6.7

P43652

Afamin

1.8 ± 1.3

1.7 ± 1.4

P35858

Insulin-like growth factor-binding protein

2.4 ±1

1.9 ± 1.2

P01019

Angiotensinogen

2.6 ± 1.9

1 ± 1.6

P01008

Antithrombin-III

5.2 ± 4.6

3.8 ± 4.2

P06727

Apolipoprotein A-IV

2.9 ± 2.8

3.4 ± 3.4

P02654

Apolipoprotein C-I

0.67 ± 0.41

1.4 ± 0.65

P02655

Apolipoprotein C-II

0.22 ± 0.25

0.44 ± 0.42

P05090

Apolipoprotein D

0.67 ± 0.5

0.44 ± 0.42

P02749

Apolipoprotein H

4.9 ±4

4.8 ± 3.8

O95445

Apolipoprotein M

0.89 ± 0.45

0.67 ± 0.5

O75882

Attractin

0.22 ± 0.25

0

P43251

Biotinidase

0.11 ± 0.19

0.22 ± 0.25

P08185

Corticosteroid-binding globulin

1 ± 0.9

0.78 ± 1

P00450

Ceruloplasmin

23.6 ± 7.6

23.1 ± 11.6

P00751

Complement factor B

4.4 ± 2.8

4.1 ± 3.3

P05156

Complement factor I

1 ± 0.9

1 ± 1.3

P06681

Complement C2

1.1 ± 0.67

0.67 ± 0.76

P01024

Complement C3

116 ± 43

139.6 ± 64 t

P01031

Complement C5

4.9 ± 2.7

4.1 ± 2.3

P13671

Complement component C6

3.3 ± 1.3

2.9 ± 1.6

P10643

Complement component C7

1.3 ± 0.87

1.6 ± 1.2

P07357

Complement component C8 alpha chain

0.22 ± 0.25

1 ± 0.87

P07358

Complement component C8 beta chain

1.2 ± 0.75

0.78 ± 0.81

P07360

Complement component C8 gamma chain

0.78 ± 0.48

0.78 ± 0.48

P02748

Complement component C9

0.78 ± 0.81

1.4 ± 1.5

P22792

Carboxypeptidase N subunit 2

0.56 ± 0.51

0.78 ± 0.56

Q16610

Extracellular matrix protein 1

0.44 ± 0.42

0.11 ± 0.19

P00748

Coagulation factor XII

1.2 ± 1.3

1.3 ± 1.1

P02765

Alpha-2-HS-glycoprotein

7.4 ± 6

6.1 ± 5.8

Q03591

Complement factor H-related protein 1

0.78 ± 0.63

0.56 ± 0.58

P06396

Gelsolin

3.6 ± 3.3

3.7 ± 4.6

P02790

Hemopexin

12.4 ± 9.9

12.9 ± 10.7

P05546

Heparin cofactor 2

1.2 ±1.3

1 ± 1

P04196

Histidine-rich glycoprotein

2.9 ±1.8

1.3 ± 1

P05155

Plasma protease C1 inhibitor

4.9 ± 2.5

4.6 ± 2.9

P19827

Inter-alpha-trypsin inhibitor heavy chain H1

7.4 ± 5.1

8.4 ± 5

Q06033

Inter-alpha-trypsin inhibitor heavy chain H3

1.1 ± 0.45

0.56 ± 0.42

Q14624

Inter-alpha-trypsin inhibitor heavy chain H4

16 ± 3.8

17.9 ± 9.8

P03952

Plasma kallikrein

1 ± 0.58

1.1 ± 0.67

P01042

Kininogen-1

5.3 ± 1.2

4.4 ± 2

P51884

Lumican

2 ± 0.65

2.4 ± 1.3

Q9NU22

Midasin

0.11 ± 0.19

0.11 ± 0.19

P36955

Pigment epithelium-derived factor

1 ±0.87

0.68 ± 1.2

Q96PD5

N-acetylmuramoyl-L-alanine amidase

1.4 ± 1.1

1.6 ± 1.5

P00747

Plasminogen

4.7 ± 5.1

6 ± 6.3

P02753

Retinol-binding protein 4

0.33 ± 0.29

0.44 ± 0.59

P35542

Serum amyloid A-4 protein

0.33 ± 0.5

0.22 ± 0.38

P02743

Serum amyloid P-component

2.4 ± 1.3

2.6 ± 1.4

P49908

Selenoprotein P

0.11 ± 0.19

0.22 ± 0.25

P04278

Sex hormone-binding globulin

0.22 ± 0.25

0.78 ± 0.9

Q8WYL5

Protein phosphatase Slingshot homolog 1

0.44 ± 0.42

0.11 ± 0.19

  1. The average scan count ± SEM is provided for each protein identified in only the HDL fraction derived from both plasma and serum. (P < 0.001; * significantly greater in plasma; † significantly greater in serum)