Table 1 Dose-dependent upregulated protein spots in response to Pb (II)
From: Characterization of proteome alterations in Phanerochaete chrysosporium in response to lead exposure
| Â | Â | Â | Treatment/Control Ratio | Â | Â | ||
|---|---|---|---|---|---|---|---|
KOG Class | Protein ID | Putative Function | 25 μM | 50 μM | 100 μM | Subcellular Locations* | Multiple Spots |
Amino acid transport and metabolism | 139320a | Isocitrate dehydrogenase, alpha subunit | 5,14 | 5,02 | 4,06 | Mit | 2 |
Carbohydrate transport and metabolism | 134115 | UDP-glucose pyrophosphorylase | 3,50 | 3,05 | 5,22 | Cyto_nuc | - |
| Â | 135471 | Septin family protein (P-loop GTPase) | New | New | New | M | - |
| Â | 132198d | Glyceraldehyde 3-phosphate dehydrogenase | - | New | New | C | 4 |
Cytoskeleton | 139298a | Actin and related proteins | 1,38 | 11,01 | 1,43 | Cysk | 4 |
Energy production and conversion | 137299d | F0F1-type ATP synthase, alpha subunit | New | New | New | Mit | 4 |
General function prediction only | 134635 | mRNA splicing factor | 2,29 | 4,62 | 2,26 | C | - |
Intracellular trafficking, secretion, and vesicular transport | 123314 | GTPase Ran/TC4/GSP1 (nuclear protein transport pathway), small G protein superfamily | New | New | New | C | - |
Lipid transport and metabolism | 1819 | Short-chain acyl-CoA dehydrogenase | 3,60 | 3,70 | 4,30 | C | - |
Posttranslational modification, protein turnover, chaperones | 8527 | Thioredoxin reductase | 2,54 | 3,49 | 4,46 | Mit | - |
RNA processing and modification | 123005a | Polyadenylate-binding protein (RRM superfamily) | New | New | New | Cysk | 2 |
| Â | 126823 | ATP-dependent RNA helicase | 0,97 | 7,89 | 1,86 | Nuc | - |
Secondary metabolites biosynthesis, transport and catabolism | 4796c | Alcohol dehydrogenase, class V | - | New | New | C | 4 |
Signal transduction mechanisms | 10373 | G protein beta subunit-like protein | 3,10 | 3,30 | 4,60 | C | - |