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Figure 5 | Proteome Science

Figure 5

From: Systems analysis of endothelial cell plasma membrane proteome of rat lung microvasculature

Figure 5

Expanded networks of mechanotransduction/mechanosignaling and adhesion. All molecules associated with each function were taken from both figure 4 and our membranome if they were not included in the top 14 networks. Protein-protein associations are indicated by single lines, whereas the arrows indicate the protein controls the other's expression. Only direct protein-protein interaction was allowed in these detailed networks, Mechanotransduction/mechanosignaling (a) and adhesion (b). Each node shape represents a different class of molecule, as shown in (c). Red nodes show that the proteins were enriched in the PM (P/H > 1.0). Green nodes indicate the depletion of the protein in P (P/H < 1.0). The darker the colors are, the greater the enrichment or depletion. White nodes indicate the proteins were not found in our dataset.

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