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Table 2 Differentially expressed proteins(PCa:BPH with local PIN)

From: Periostin identified as a potential biomarker of prostate cancer by iTRAQ-proteomics analysis of prostate biopsy

Accession

Protein name

Peptides(95%)

116:117

Down-regulation

sp|P17661

Desmin

62

0.03

sp|P24844

Myosin regulatory light polypeptide 9

10

0.14

sp|O95810

Serum deprivation-response protein 3

3

0.16

sp|Q9BX66

Sorbin and SH3 domain-containing protein 1

18

0.20

sp|P09493

Tropomyosin alpha-1 chain

60

0.21

sp|Q969G5

Protein kinase C delta-binding protein

6

0.28

sp|P51911

Calponin-1

43

0.29

sp|P18206

Vinculin

15

0.30

sp|P15309

Prostatic acid phosphatase

4

0.32

sp|Q15942

Zyxin

4

0.36

sp|P02671

Fibrinogen alpha chain

18

0.37

sp|P07305

Histone H1.0

6

0.37

sp|Q9Y490

Talin-1

21

0.50

sp|P30101

Protein disulfide-isomerase A3

33

0.58

Up-regulation

sp|Q09666

Neuroblast differentiation-associated protein AHNAK

62

1.91

sp|P00367

Glutamate dehydrogenase 1, mitochondrial

10

2.19

sp|P13667

Protein disulfide-isomerase A4

5

2.19

sp|P10606

Cytochrome c oxidase subunit 5B, mitochondrial

7

2.31

sp|P12111

Collagen alpha-3(VI) chain

63

2.33

sp|P31943

Heterogeneous nuclear ribonucleoprotein H

3

2.42

sp|P61604

10 kDa heat shock protein, mitochondrial

9

2.44

sp|P49411

Elongation factor Tu, mitochondrial

6

2.86

sp|P11021

78 kDa glucose-regulated protein

27

2.93

sp|P35579

Myosin-9

29

3.25

sp|P07237

Protein disulfide-isomerase

17

3.44

sp|P21810

Biglycan

19

3.53

sp|P22392

Nucleoside diphosphate kinase B

5

3.73

sp|P10809

60 kDa heat shock protein, mitochondrial

25

5.55

sp|Q15063

Periostin

13

5.55

sp|P62906

60S ribosomal protein L10a

6

5.97

sp|P06748

Nucleophosmin

10

6.37

sp|Q9BXN1

Asporin

7

7.38

sp|Q00796

Sorbitol dehydrogenase

9

9.12

  1. *The proteins written with bold words were the same differentially expressed proteins between 116:114(PCa:BPH) and 116:117(PCa:BPH with local PIN).