Figure 3From: Impact of clostridial glucosylating toxins on the proteome of colonic cells determined by isotope-coded protein labeling and LC-MALDI rTcdA glucosylates Rac-1 in Caco-2 cells. The cytopathic effect was shown by a Rac-1 glucosylation sensitive western blot analysis. The used antibody did not bind to glucosylated Rac-1. 1 and 4: control cells; 2 and 5: rTcdA wt treated cells; 3 and 6: mutant rTcdA treated cells.Back to article page