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Table 1 Current Available Validated Antibodies for Protein Kinases and Regulators

From: Improved protein arrays for quantitative systems analysis of the dynamics of signaling pathway interactions

AKT

Rb

NFkBp65

pAKT(S473)

pRb(S807_811)

pNFkBp65(S536)

pAKT(T308)

p16

IKBa

ERK1/2

p21

pIKBa(S32)

pERK1/2(S44/42)

p27

MDM2

GSK3ab

CyclinB1

pMDM2(S166)

pGSK3ab(S21/9)

CyclinD3

E-Cadherin

IRS1

Cdk4

Vimentin

pIRS1(Y896)

EGFR

b-Catenin

pIRS1(Y1179)

pEGFR(Y1173)

gH2AX

mTOR

IGF1R

Hsp27

pmTOR(S2448)

pIGF1R(Y1158_1162)

NQO1

PTEN

pIGF1R(Y1162_1163)

sClu

pPTEN(S380)

Raf1

b-Actin

p38

pRaf1(S259)

Smad3

pp38(T180_Y182)

Bcl2

pSmad3(S423/425)

Src

pBcl-2(S70)

Cleaved Caspase 3

pSrc(Y416)

JNK

Cleaved Caspase 8

pSrc(Y527)

pJNK(T183_185)

Cleaved Caspase 9

Stat3

p53

 

pStat3(S727)

pp53(S15)