Table 1 Current Available Validated Antibodies for Protein Kinases and Regulators
AKT | Rb | NFkBp65 |
|---|---|---|
pAKT(S473) | pRb(S807_811) | pNFkBp65(S536) |
pAKT(T308) | p16 | IKBa |
ERK1/2 | p21 | pIKBa(S32) |
pERK1/2(S44/42) | p27 | MDM2 |
GSK3ab | CyclinB1 | pMDM2(S166) |
pGSK3ab(S21/9) | CyclinD3 | E-Cadherin |
IRS1 | Cdk4 | Vimentin |
pIRS1(Y896) | EGFR | b-Catenin |
pIRS1(Y1179) | pEGFR(Y1173) | gH2AX |
mTOR | IGF1R | Hsp27 |
pmTOR(S2448) | pIGF1R(Y1158_1162) | NQO1 |
PTEN | pIGF1R(Y1162_1163) | sClu |
pPTEN(S380) | Raf1 | b-Actin |
p38 | pRaf1(S259) | Smad3 |
pp38(T180_Y182) | Bcl2 | pSmad3(S423/425) |
Src | pBcl-2(S70) | Cleaved Caspase 3 |
pSrc(Y416) | JNK | Cleaved Caspase 8 |
pSrc(Y527) | pJNK(T183_185) | Cleaved Caspase 9 |
Stat3 | p53 | Â |
pStat3(S727) | pp53(S15) | Â |