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Table 1 Number of differentially expressed proteins and protein isoforms in striatum, midbrain and cortex tissues of PINK1-KO mice compared to wild-type mice

From: Brain region specific mitophagy capacity could contribute to selective neuronal vulnerability in Parkinson's disease

Brain region Differentially expressed protein isoforms* Identified protein isoforms Number of corresponding genes
striatum 173 (95↑, 78↓) 100 20
midbrain 62 (11↑, 51↓) 57 30
cortex 82 (75↑, 7↓) 70 28
  1. Over 5000 protein spots were investigated (Student's t-test, p < 0.05, changes over 20% vs. wildtype control).
  2. *: ↑, up-regulated; ↓, down-regulated.