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Table 1 Number of differentially expressed proteins and protein isoforms in striatum, midbrain and cortex tissues of PINK1-KO mice compared to wild-type mice

From: Brain region specific mitophagy capacity could contribute to selective neuronal vulnerability in Parkinson's disease

Brain region

Differentially expressed protein isoforms*

Identified protein isoforms

Number of corresponding genes

striatum

173 (95↑, 78↓)

100

20

midbrain

62 (11↑, 51↓)

57

30

cortex

82 (75↑, 7↓)

70

28

  1. Over 5000 protein spots were investigated (Student's t-test, p < 0.05, changes over 20% vs. wildtype control).
  2. *: ↑, up-regulated; ↓, down-regulated.
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Proteome Science

ISSN: 1477-5956