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Table 3 Topmost five preferred residue pairs at the binding sites of protein-protein, protein-RNA and protein-DNA complexes

From: Sequence and structural features of binding site residues in protein-protein complexes: comparison with protein-nucleic acid complexes

Protein-protein Protein-RNA Protein-DNA
*B
ASP TRP CYS TRP SER ARG
CYS TRP HIS ARG GLY ARG
ILE TRP ASN ARG LYS ARG
MET TRP ILE TYR ARG ARG
MET TYR TRP ARG CYS TRP
B*
CYS TRP HIS TRP ARG SER
MET TRP HIS HIS ARG GLY
TRP PHE HIS ARG ASN TRP
TRP HIS LYS HIS ARG LYS
TRP MET MET TRP ARG ASN
  1. B: Binding. The binding residue are underlined.