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Table 4 Average computation time to create a profile by PSI-BLAST using sequences of different length as input. In Scheme I, full-length sequences are presented to PSI-BLAST and the resulting profiles are truncated at the predicted cleavage sites. In Scheme II, truncation is applied to the sequences before presenting to PSI-BLAST. In both cases, CRFs (CSitePred) were used to predict the cleavage sites.

From: Fast subcellular localization by cascaded fusion of signal-based and homology-based methods

Scheme

Input to PSI-BLAST

Profile Creation Time (second)

Subcellular Localization Accuracy

I

Full-length sequences

30.5

91.69%

II

Sequences truncated at predicted cleavage sites

4.7

91.45%