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Table 4 Average computation time to create a profile by PSI-BLAST using sequences of different length as input. In Scheme I, full-length sequences are presented to PSI-BLAST and the resulting profiles are truncated at the predicted cleavage sites. In Scheme II, truncation is applied to the sequences before presenting to PSI-BLAST. In both cases, CRFs (CSitePred) were used to predict the cleavage sites.

From: Fast subcellular localization by cascaded fusion of signal-based and homology-based methods

Scheme Input to PSI-BLAST Profile Creation Time (second) Subcellular Localization Accuracy
I Full-length sequences 30.5 91.69%
II Sequences truncated at predicted cleavage sites 4.7 91.45%