Table 1 Proteomic identification of brittle star matrix proteins in gastrula
Ophiocoma wendtii ID | Domains identified, possible homology | NCBI entry [Sea Urchin] top hits | Presence in sea urchin skeletal proteome | Designation |
|---|---|---|---|---|
Extracellular matrix components | Â | Â | Â | Â |
LUPK | C-Type Lectin | XP_003730279.1 | C-Type lectins found in all | SM22 |
266 | C-Type Lectin | XP_003730279.1 | C-Type lectins found in all | SM24 |
1464 | C-Type Lectin | XP_790287.2 | C-Type lectins found in all | SM21 |
358 | Syndecan/SEA domain | NP_00118233.1 | Spicule | Â |
PO24 | Fibrinogen C | XP_781712.2 | Spicule and tooth | Â |
Protease and protease inhibitor domains | Â | Â | Â | |
998 | Agrin; Kazal Inhibitor | XP_791472.3 | Test and tooth | Â |
2557 | Agrin; Kazal Inhibitor | XP_003724092.1 | Test and Tooth | Â |
NAKRO | Matrix Metalloproteinase | XP_791616.2 | MMP's found in all | Â |
2581 | Alpha-2-macroglobulin | XP_788246.3 | Found in all | Â |
Other proteins identified | Â | Â | Â | |
149 | Calmodulin | XP_780862.2 | Test and Tooth | Â |
M7PKJ | LDL receptor-like | XP_794505.3 | Found in all | Â |
LI454 | LDL receptor-like | XM_003729261.1 | Found in all | Â |
8435 | Defense protein 3-like | XP_789043.2 | Not present | Â |
KGGQ | Tetraspanin-like | XP_003726229.1 | Spicule and Tooth | Â |
FEQQ | LVN-1-like | XM_003723550.1 | Not present | Â |
12396 | Actin | XP_001176242.1 | Found in all | Â |
144 | Actin | NP_999634.1 | Found in all | Â |
14123 | Actin | P53472.1 | Found in all | Â |
1QFC/3S4M | Collagen | NP_999675.1 | Found in all | Â |
7694 | Glut peptide cyclotransferase | XP_003726229.1 | Spicule and Tooth | Â |
10842 | Tubulin | XP_791790.1 | Test and Spine | Â |
83/1103/2063/4032 | Ubiquitin | P23398.2 | Found in all | Â |