Table 1 Mouse saliva proteins involved in host defense and wound healing

Q14BX6

4933415F23Rik

innate immune response; regulation of phosphorylation

P29699

Ahsg

positive regulation of phagocytosis; regulation of inflammatory response

Q61176

Arg1

response to interleukin-4, lipopolysaccharide, transforming growth factor beta

P01887

B2m

defense response; phagocytic vesicle membrane; positive regulation of T cell mediated cytotoxicity; response to bacteria

P97361

Bpifa1

antibacterial humoral response; innate immune response

Q61114

Bpifb1

innate immune response

P01027

C3

complement activation; inflammatory response; positive regulation of phagocytosis

Q91XA9

Chia

immune system process; positive regulation of chemokine secretion

O35744

Chil3

inflammatory response

P11087

Col1a1

response to transforming growth factor beta stimuli; tooth mineralization; wound healing

O88207

Col5a1

cell adhesion; collagen biosynthetic process; extracellular fibril organization; wound healing

Q9WVJ3

Cpq

carboxypeptidase activity; metallodipeptidase activity; proteolysis; tissue regeneration

P21460

Cst3

cellular response to hydrogen peroxide, axon injury, hypoxia; response to nutrient levels; response to toxic substance

P13020

Gsn

actin filament polymerization; aging; cilium morphogenesis; regulation of cell adhesion; tissue regeneration

Q61646

Hp

antioxidant activity; defense response to bacterium; immune system process; response to hypoxia

O35664

Ifnar2

response to interferon-alpha; type I interferon receptor activity; type I interferon signaling pathway

P01592

Igj

adaptive immune response; antibacterial humoral response; innate immune response

Q9Z1M2

Irgm2

defense response to bacterium; defense response to protozoan; response to interferon-gamma

P00755

Klk1b1

bradykinin biosynthetic process; tissue kallikrein-kinin cascade; vasodilation

P26262

Klkb1

blood coagulation; fibrinolysis; inflammatory response; plasminogen activation;

Q61805

Lbp

defense response to Gram-negative/Gram positive bacterium; innate immune response; regulation of chemokine production

Q5SW46

Lpo

defense response to bacterium; peroxidase activity; response to oxidative stress

P08071

Ltf

antibacterial humoral response; antifungal humoral response; innate immune response in mucosa; positive regulation of toll-like receptor 4 signaling pathway; regulation of cytokine production; regulation of tumor necrosis factor production

P17897

Lyz1

cytolysis; defense response to Gram-negative/ Gram-positive bacterium; lysozyme activity

E9Q5I3

Muc5b

defense response to bacterium; regulation of macrophage activation

Q6LDU8

Ngf

inflammatory response; response to lipopolysaccharide; response to radiation; sensory perception of pain

O08692

Ngp

defense response

O88593

Pglyrp1

defense response to Gram-positive bacterium; innate immune response; negative regulation of inflammatory response; negative regulation of interferon-gamma production; negative regulation of natural killer cell differentiation

P02816

Pip

aspartic-type endopeptidase activity; regulation of immune system process

O09049

Reg3g

MyD88-dependent toll-like receptor signaling pathway; defense response to Gram-positive bacterium; positive regulation of wound healing

P31725

S100a9

chronic inflammatory response; innate immune response; leukocyte chemotaxis; neutrophil aggregation; response to lipopolysaccharide

P07758

Serpina1a

acute-phase response; response to cytokine; response to peptide hormone

Q80YQ1

Thbs1

cellular response to growth factor stimulus; cellular response to tumor necrosis factor; chronic inflammatory response; immune response; inflammatory response

Q9JHY3

Wfdc12

defense response to bacterium; extracellular region; serine-type endopeptidase inhibitor activity

P63101

Ywhaz

histamine secretion by mast cell; response to drug