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Table 3 Sex-linked proteins.

From: Towards further defining the proteome of mouse saliva

UniProt

Protein name

Gene symbol

Gene ontology (GO)

A) Salivary proteins unique to male mice

Q9D6P8

Calmodulin-like protein 3

Calml3

calcium ion binding

Q8BHN3

Neutral alpha-glucosidase AB

Ganab

Golgi apparatus; N-glycan processing; carbohydrate binding; endoplasmic reticulum; glucan 1,3-alpha-glucosidase activity; glucosidase II complex; glucosidase activity; melanosome; protein binding

Q91XA2

Golgi membrane protein 1

Golm1

Golgi apparatus; integral component of membrane; nucleus organization; regulation of lipid metabolic process

Q61754

Kallikrein 1-related peptidase b24

Klk1b24

proteolysis; serine-type endopeptidase activity

Q63836

Selenium-binding protein 2

Selenbp2

cytosol; membrane; nucleus; protein transport; selenium binding

P70277

Alpha-N-acetylgalactosaminide alpha-2,6-sialyltransferase 2

St6galnac2

integral component of Golgi membrane; protein glycosylation; sialyltransferase activity

B1AQJ2

Ubiquitin carboxyl-terminal hydrolase 36

Usp36

cysteine-type peptidase activity; nucleolus; ubiquitin-dependent protein catabolic process

Q80YQ1

Thrombospondin 1

Thbs1

activation of MAPK activity; blood vessel morphogenesis; calcium ion binding; cell adhesion; cell cycle arrest; cell migration; cellular response to growth factor stimulus; cellular response to tumor necrosis factor; (abbreviated)

J3QM75

MCG1039283 (Protein Scgb2b19)

Scgb2b19

extracellular space

A2ANT6

Major urinary protein 6

Mup6

extracellular region; pheromone binding; small molecule binding; transporter activity

B) Salivary proteins unique to female mice

P29699

Alpha-2-HS-glycoprotein

Ahsg

acute-phase response; cysteine-type endopeptidase inhibitor activity; extracellular space; negative regulation of bone mineralization; ossification; positive regulation of phagocytosis; regulation of inflammatory response

Q5GAN1

Angiogenin ribonuclease 5

Ang5

endoribonuclease activity, producing 3'-phosphomonoesters; nucleic acid binding

  1. Ten proteins found in mouse saliva were limited to males and 2 proteins were limited to females. Gene ontologies were derived from UniProt.