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Fig. 5 | Proteome Science

Fig. 5

From: Alteration of actin dependent signaling pathways associated with membrane microdomains in hyperlipidemia

Fig. 5

Immunological validation of mass spectrometry data for beta-actin and vinculin. Protein expression of beta-actin (actin cytoplasmatic 1) and vinculin was detected in membrane microdomains enriched fractions by Western Blotting (a and c respectively), confirming the alteration caused by the hyperlipidemic condition (A) and statin treatment (At) when compared to the control samples (C), detected by LC-MS/MS analysis (b and d respectively). The Western Blotting experiments were repeated three times. Data are expressed as means ± SD. **p < 0.01, ***p < 0.001

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Proteome Science

ISSN: 1477-5956