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Table 2 IC 50 values of the synthetic analogues of natural BPPs for the angiotensin converting enzyme

From: Isolation and characterization of Bradykinin potentiating peptides from Agkistrodon bilineatus venom

Peptide

Sequence

Calculated pI value

IC 50 (μM)

Inhibitor 1 (P6)

ZLWPRPQXPP

9.75

0.64

Inhibitor 2 (P7)

ZQWAQGRAPHPP

9.78

3.63

Inhibitor 3 (P5)

ZSAPGNEAXPP

3.99

30.00

Inhibitor 4 (P3)

ZNWPHPQXPP

6.74

0.76

  1. Z in stands for pyroglutamate; X refers to isoleucine/leucine