Table 3 Representation of CaOx stone proteins by molecular class (≥5)
From: Label-free proteomic methodology for the analysis of human kidney stone matrix composition
Protein Molecular Class | # of unique proteins identified |
|---|---|
Cytoskeletal & associated protein; structural protein | 75 |
Transport/cargo protein | 49 |
Chaperone/Heat shock protein | 36 |
Ribonucleoprotein; RNA binding protein | 35 |
Extracellular matrix protein | 31 |
Transcription factor or regulatory protein | 29 |
Enzyme: Hydrolase | 27 |
Translation regulatory protein | 27 |
G protein; GTPase & associated | 26 |
Immunoglobulin | 24 |
Unclassified | 24 |
Ribosomal subunit | 23 |
Adhesion molecule | 21 |
Enzyme: dehydrogenase | 21 |
Ubiquitin proteasome system | 21 |
Complement protein | 20 |
Protease inhibitor | 19 |
Adapter molecule | 18 |
Calcium binding protein | 18 |
Secreted polypeptide | 18 |
Coagulation factor | 16 |
Cysteine protease | 15 |
DNA binding protein | 15 |
Integral membrane protein | 15 |
Serine/threonine kinase or phosphatase | 15 |
Enzyme: Ligase | 14 |
Enzyme: Oxidoreductase | 14 |
Cell surface receptor | 12 |
Enzyme: Phosphotransferase | 12 |
Serine protease | 9 |
Enzyme: Isomerase | 7 |
Enzyme: Peroxidase | 6 |
Membrane transport protein | 6 |
MHC complex protein | 6 |
ATPase | 5 |
Enzyme: Reductase | 5 |