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Table 3 Validation of pathways affected by in difference expression protein by the different metabolic detected by 1H NMR (Y1 compared with Y2)

From: Multi-omics analysis on the pathogenicity of Enterobacter cloacae ENHKU01 isolated from sewage outfalls along the Ningbo coastline

The condition of regulated by proteins Pathways Upregulated Metabolites
Y1 Y2
Y1 upregulated Two-component system 1a 2b
Y2 upregulated ABC transporters 2c 9d
Glycine, serine and threonine metabolism - 4g
Methane metabolism - 5h
Pentose phosphate pathway - 1l
Phenylalanine metabolism - 4k
Pyrimidine metabolism 1e 5f
Y1 and Y2 Co-regulated Bacterial chemotaxis - -
Bacterial secretion system - -
Glycolysis / Gluconeogenesis 1i 2j
  1. aGlutamate. bSuccinate, Fumarate. cGlutamate, 2-Alanine. dAlanine, Betaine, Glycine, Isoleucine, Leucine, Methionine, Phenylalanine, Valine, Threonine. e2-Alanine. fAlanine, Thymine, Uracil, Cytosine, Uridine. gBetaine, Glycine, Pyruvate, Threonine. hGlycine, Acetate, Formate, Pyruvate, Methanol. iLactate. jAcetate, Pyruvate. kPhenylalanine, Succinate, Fumarate, Pyruvate. lPyruvate