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Table 5 Verify pathways affected by in difference expression protein by the different metabolic detected by 1H NMR (Y2 compared with Y3)

From: Multi-omics analysis on the pathogenicity of Enterobacter cloacae ENHKU01 isolated from sewage outfalls along the Ningbo coastline

The condition of regulated by proteins

Pathways

Upregulated Metabolites

Y2

Y3

Y3 upregulated

Bacterial secretion system

-

-

Glycolysis/Gluconeogenesis

-

-

Pentose phosphate pathway

-

-

Pyruvate metabolism

-

1a

Citrate cycle

-

1b

ABC transporters

1c

6d

Y2 and Y3 Co-regulated

Phenylalanine metabolism

1e

-

Glycine, serine and threonine metabolism

1f

3g

Glutathione metabolism

-

2h

Phosphotransferase system

-

-

Nicotinate and nicotinamide metabolism

-

-

Pyrimidine metabolism

-

-

Purine metabolism

-

-

  1. aFumarate. bFumarate. cBetaine. dAspartate, Glutamate, Glycine, Leucine, Lysine, Choline. eFumarate. fBetaine. gAspartate, Glycine, Choline. hGlutamate, Glycine