iTRAQ-based proteomic analysis of myofibrillar contents and relevant synthesis and proteolytic proteins in soleus muscle of hibernating Daurian ground squirrels (Spermophilus dauricus)

Chang, Hui; Jiang, Shan-Feng; Dang, Kai; Wang, Hui-Ping; Xu, Shen-Hui; Gao, Yun-Fang

doi:10.1186/s12953-016-0105-x

Proteome Science

Table 2 Summary table showing significantly up-regulated or down-regulated proteins with protein proteolysis function in SOL of Daurian ground squirrels identified by iTRAQ

From: iTRAQ-based proteomic analysis of myofibrillar contents and relevant synthesis and proteolytic proteins in soleus muscle of hibernating Daurian ground squirrels (Spermophilus dauricus)

Acc no. (NCBI)	Prot name [Ictidomys tridecemlineatus]	MW (Da)	Peptide	Score	60-d hibernation vs pre-hibernation		Post-hibernation vs pre-hibernation		Post-hibernation vs 60-d hibernation
Acc no. (NCBI)	Prot name [Ictidomys tridecemlineatus]	MW (Da)	Peptide	Score	Fold change	Sig	Fold change	Sig	Fold change	Sig
Up-regulated proteins
gi\|532073955	proteasome subunit alpha type-6	28470	8	480	1.23	*	1.248	*
gi\|532105099	proteasome subunit alpha type-5	30824	7	614	1.226	*	1.226	*
gi\|59800155	26S protease regulatory subunit 10B	53861	7	589	1.281	*	1.264	*
gi\|532070252	26S proteasome non-ATPase regulatory subunit 5 isoform X1	63125	2	46	1.517	*
gi\|532091148	26S proteasome non-ATPase regulatory subunit 4	48541	5	133	1.488	*
gi\|532103645	proteasome subunit beta type-6 isoform X1	27252	3	115	1.295	*
gi\|532073989	proteasome subunit alpha type-3 isoform X1	34727	5	462	1.209	*
gi\|532066291	cytosol aminopeptidase	66612	11	731	1.202	*
gi\|532101732	26S protease regulatory subunit 6B isoform X1	56577	4	375	1.246	*
gi\|532088665	26S protease regulatory subunit 6A	60713	9	638	1.32	*
gi\|532080894	calpastatin	113441	7	179			1.226	*
gi\|532073188	endoplasmin	117277	14	399			1.316	*
gi\|532076563	ubiquitin-like modifier-activating enzyme 1 isoform X2	135211	19	1304			1.242	*
gi\|532069763	xaa-Pro aminopeptidase 1-like isoform X1	88255	5	128			1.485	*
gi\|532062055	proteasome subunit alpha type-4	37964	6	247			1.289	*
gi\|532114683	calpain small subunit 1	31666	4	257			1.301	*	1.488	*
gi\|532105581	ubiquitin carboxyl-terminal hydrolase 5 isoform X1	112519	10	369			1.221	*
gi\|532082471	acylamino-acid-releasing enzyme	91596	7	160			1.567	*
gi\|532088974	prolyl endopeptidase	95929	11	396			1.385	*
gi\|532078165	ubiquitin carboxyl-terminal hydrolase isozyme L3	30900	4	212			1.591	*	1.552	*
gi\|532097874	ubiquitin fusion degradation protein 1 homolog isoform X1	41760	5	206			1.419	*
gi\|532116708	proteasome subunit beta type-1	30778	7	506					1.283	*
gi\|532085114	26S proteasome non-ATPase regulatory subunit 12 isoform X1	66713	4	67					1.457	*
Down-regulated proteins
gi\|532064840	ubiquinone biosynthesis protein COQ9, mitochondrial	38864	6	713	0.811	*
gi\|532078642	poly(rC)-binding protein 2 isoform X1	54651	5	470	0.732	*
gi\|532086828	cullin-5	114587	6	160	0.774	*

Acc no. (Accession number), Prot name (protein name), MW (Molecular mass), Peptide (number of peptides matched), Score (Mowse score), Sig (*P-value < 0.05 was considered statistically significant)

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