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Table 3 Summary table showing significantly up-regulated or down-regulated proteins of structural constituent of SOL muscle in Daurian ground squirrels identified by iTRAQ

From: iTRAQ-based proteomic analysis of myofibrillar contents and relevant synthesis and proteolytic proteins in soleus muscle of hibernating Daurian ground squirrels (Spermophilus dauricus)

Acc no. (NCBI) Prot name [Ictidomys tridecemlineatus] MW (Da) Peptide Score 60-d hibernation vs pre-hibernation Post-hibernation vs pre-hibernation Post-hibernation vs 60-d hibernation
Fold change Sig Fold change Sig Fold change Sig
Up-regulated proteins   
 gi|532098453 small muscular protein isoform X2 12381 3 504 1.238 * 1.392 *   
 gi|532095619 cofilin-1 26628 7 639 1.239 * 1.535 *   
 gi|532065022 tubulin polymerization-promoting protein family member 3 27600 2 147 1.607 * 1.481 *   
 gi|532085001 myosin light chain 4 isoform X2 27241 6 968 1.434 * 1.579 *   
 gi|532097561 myelin basic protein 44089 2 69 1.456 *     
 gi|532069819 nebulin-related-anchoring protein 245551 22 744 1.211 *     
 gi|532094579 myosin-2 244418 102 66551 2.135 *     
 gi|532087098 PDZ and LIM domain protein 3 isoform X1 45822 12 3700 1.304 *     
 gi|532062716 troponin C 22795 11 5693 1.358 *     
 gi|532080240 vimentin 54132 26 3859 1.211 *    1.828 *
 gi|532089364 myosin-binding protein H 60653 11 835    1.696 *   
 gi|532081847 zyxin 72401 2 97    1.371 *   
 gi|532111896 tubulin alpha-8 chain isoform X1 60805 15 2177    1.355 *   
 gi|532063429 F-actin-capping protein subunit beta isoform X2 36610 11 763    1.219 *   
 gi|532074211 nidogen-2 isoform X1 165553 7 164    1.467 *   
 gi|532076843 myozenin-3 30065 6 801    1.401 *   
 gi|532100104 myosin light polypeptide 6 isoform X1 20132 8 2096    1.576 *   
 gi|532099239 moesin-like 87289 14 565    1.248 *   
 gi|532103138 myosin regulatory light chain 12B 24691 6 374    1.771 *   
 gi|532081115 talin-1 321070 21 790    1.288 * 1.302 *
 gi|532088445 myosin regulatory light polypeptide 9 isoform X1 24375 5 323    1.68 *   
 gi|532095126 PDZ and LIM domain protein 7 60050 6 361    1.653 *   
 gi|532111349 ankyrin-1 isoform X1 242338 33 1740    2.69 *   
 gi|532098546 tubulin beta-5 chain-like 46713 12 1245    1.367 *   
 gi|532061621 annexin A2 49151 21 2021    1.502 *   
 gi|532068053 myocilin 59868 4 159    2.837 *   
 gi|532100974 neurofilament heavy polypeptide 158649 7 679    1.55 *   
 gi|532110489 neurofilament medium polypeptide 123496 7 571    1.677 *   
 gi|532089731 tubulin alpha-4A chain 56718 18 3110    1.396 *   
 gi|532089733 tubulin alpha-1D chain-like 57019 18 3316    2.103 *   
 gi|532063781 protein 4.1 isoform X1 120337 9 505    2.552 *   
 gi|532111734 alpha-actinin-4 isoform X1 125310 18 2664    1.228 *   
 gi|532072736 beta-adducin isoform X1 100809 3 84    1.759 *   
 gi|532083652 tubulin beta-2A chain isoform X1 56576 21 2455    1.637 * 1.687 *
 gi|532081219 tropomodulin-1 49085 4 141      1.509 *
 gi|532102653 tubulin beta-4B chain isoform X1 55122 22 3594      1.25 *
 gi|532062201 fibrillin-1 340347 14 616      1.685 *
Down-regulated proteins   
 gi|532094519 myosin-3 287961 49 33292 0.587 * 0.399 * 0.758 *
 gi|532085261 transgelin isoform X2 28099 11 691 0.784 *     
 gi|532062201 fibrillin-1 340347 14 616 0.534 *     
 gi|532072041 telethonin 21240 8 817 0.811 *     
 gi|532081219 tropomodulin-1 49085 4 141 0.701 *     
 gi|532103167 actin 48418 23 58752    0.823 * 0.806 *
 gi|532059726 xin actin-binding repeat-containing protein 2-like 476702 6 84    0.774 *   
 gi|532069819 nebulin-related-anchoring protein 245551 22 744    0.747 *   
 gi|532094510 myosin-13 285781 37 26764    0.478 *   
 gi|532077683 kelch-like protein 41 85237 21 1666    0.772 *   
 gi|532097391 supervillin 300575 12 302    0.789 *   
 gi|532112765 cytoplasmic dynein 1 heavy chain 1 620997 16 383    0.807 *   
 gi|532113339 obscurin, partial 143269 19 783    0.829 *   
 gi|532112836 flotillin-1 56752 3 161    0.806 *   
 gi|532062845 filamin-B 333949 10 1568    0.743 *   
 gi|532094579 myosin-2 244418 102 66551      0.482 *
  1. Acc no. (Accession number), Prot name (protein name), MW (Molecular mass), Peptide (number of peptides matched), Score (Mowse score), Sig (*P-value < 0.05 was considered statistically significant)