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Table 1 Proteins identified from conditioned (3DHL, 3DH) and unconditioned (FP) PEMs

From: The hepatocyte proteome in organotypic rat liver models and the influence of the local microenvironment

Description

UniProt ID

Unique peptides

3DHL/FP (p-value)

3DH/FP (p-value)

Collagen alpha-1 (I), Col1a1

P02454

258

1.34 ± 0.18 (0.64)

1.30 ± 0.06 (0.46)

Collagen alpha-2 (I), Col1a2

P02466

198

1.06 ± 0.08 (0.72)

1.08 ± 0.05 (0.59)

Collagen alpha-1 (III), Col3a1

P13941

173

1.07 ± 0.06 (0.78)

1.17 ± 0.13 (0.56)

Protein Col28a1

D3ZN64

126

1.36 ± 0.08 (0.63)

1.56 ± 0.21 (0.76)

Protein Col4a2

F1M6Q3

125

1.43 ± 0.07 (0.58)

1.35 ± 0.08 (0.49)

Collagen alpha-1 (II), Col2a1

P05539

74

1.21 ± 0.02 (0.82)

1.21 ± 0.14 (0.94)

Collagen alpha-1 (XI)

P20909

69

1.03 ± 0.18 (0.92)

1.19 ± 0.49 (0.70)

Procollagen alpha-2 (XI), Col11a2

Q6MGB2

61

1.50 ± 0.16 (0.67)

1.58 ± 0.16 (0.44)

Procollagen alpha-1 (VII), Col7a1

D3ZE04

54

0.71 ± 0.33 (0.63)

0.80 ± 0.45 (0.69)

Protein Col4a5

F1LUN5

50

1.26 ± 0.02 (0.76)

1.24 ± 0.03 (0.62)

Protein Col5a2

F1LQ00

44

0.66 ± 0.58 (0.66)

0.40 ± 0.52 (1.00)

Protein Col4a1

F1MA59

39

0.74 ± 0.18 (0.65)

0.73 ± 0.23 (0.57)

Collagen alpha-1 (XXVII), Col27a1

Q80ZF0

31

0.95 ± 0.17 (0.78)

0.94 ± 0.02 (0.57)

Protein Col10a1

A0A0G2K7A5

29

1.16 ± 0.05 (0.70)

1.21 ± 0.01 (0.54)

Procollagen alpha-1 (V), Col5a1

G3V763

15

1.47 ± 0.11 (0.63)

1.53 ± 0.10 (0.44)

Protein Col14a1

D3ZZT9

14

0.51 ± 0.09 (0.70)

0.44 ± 0.06 (0.52)

Fibromodulin

P50609

5

0.32 ± 0.06 (0.95)

0.29 ± 0.02 (0.83)

  1. Ratios were calculated based on the Top 3 method as described in the experimental section. Unique peptides represent the sum total of identifications across all samples