Proteomic identification of moesin upon exposure to acrolein

Lee, Pureun-Haneul; Kim, Byeong-Gon; Lee, Sun-Hye; Leikauf, George D.; Jang, An-Soo

doi:10.1186/s12953-017-0130-4

Proteome Science

Table 2 List of proteins identified by MALDI-TOF MS analysis – 30 nM 24 h

From: Proteomic identification of moesin upon exposure to acrolein

No.	Protein name	Abbreviation	Accession no.	Amino acid sequence	pI/molecular mass (Da)	Normalized relative intensity			Ratio	p-value	Function
No.	Protein name	Abbreviation	Accession no.	Amino acid sequence	pI/molecular mass (Da)	Untreat		Treat(24 h)	Ratio	p-value	Function
Group 1
1	adenylyl cyclase-associated protein	CAP	178,084	R.SALFAQINQGESITHALK.H	51.926/8.07	0.155175	<	0.255949	1.64942	0.000459	Catalyzing reduction
2	Annexin A5	ANXA5	113,960	K.GLGTDEESILTLLTSR.S	35.971/4.94	0.215959	<	0.530059	2.45445	0.000099	Signal transduction
3	14–3-3 protein epsilon isoform	YWHAE	902,787	K.VAGMDVELTVEER.N	29.326/4.63	0.257559	<	0.601467	2.33526	6.5816E-9	Signal transduction
4	phospholipase A2	PLA2	189,953	K.FLIPNASQAESK.V	27.899/4.73	0.363461	<	0.822213	2.26218	0.000102	Protein modification
5	initiation factor 4D	eIF-4D	181,997	K.VHLVGIDIFTGK.K	17.049/5.08	0.309087	<	0.467838	1.51361	0.000093	Signal transduction
6	fibrin beta		223,002	K.HQLYIDETVNSNIPTNLR.V	51.358/7.95	0.594501	<	0.372705	1.59509	0.000108	Coagulation
Group 2
7	Tropomyosin beta chain	TPM2	136,090	R.KLVILEGELER.S	32.945/4.66	0.296457	<	1.09976	3.70968	5.8027E-7	Cytoskeleton
8	vimentin	VIM	340,219	R.ETNLDSLPLVDTHSKR.T	53.738/5.03	0.159818	<	0.858538	5.37197	0.000118	Cytoskeleton
Group 3
9	glyceraldehyde-3-phosphate dehydrogenase	GAPDH	31,645	K.LISWYDNEFGYSNR.V	36.202/8.26	0.835329	>	0.395561	0.47354	0.000003	Catalyzing reduction
10	Glutathione S-transferase P	GST-π	121,746	R.TLGLYGKDQQEAALVD MVNDGVEDLR.C	23.569/5.43	0.40715	>	0.149978	0.36836	0.000013	Antioxidation
Group 4
11	Glutathione S-transferase P	GST-π	121,746	R.TLGLYGKDQQEAALVD MVNDGVEDLR.C	23.569/5.43	0.296094	>	0.093522	0.31585	0.000076	Antioxidation

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