TY - JOUR AU - Spanos, Christos AU - Maldonado, Elaina M. AU - Fisher, Ciarán P. AU - Leenutaphong, Petchpailin AU - Oviedo-Orta, Ernesto AU - Windridge, David AU - Salguero, Francisco J. AU - Bermúdez-Fajardo, Alexandra AU - Weeks, Mark E. AU - Evans, Caroline AU - Corfe, Bernard M. AU - Rabbani, Naila AU - Thornalley, Paul J. AU - Miller, Michael H. AU - Wang, Huan AU - Dillon, John F. AU - Quaglia, Alberto AU - Dhawan, Anil AU - Fitzpatrick, Emer AU - Bernadette Moore, J. PY - 2018 DA - 2018/02/14 TI - Proteomic identification and characterization of hepatic glyoxalase 1 dysregulation in non-alcoholic fatty liver disease JO - Proteome Science SP - 4 VL - 16 IS - 1 AB - Non-alcoholic fatty liver disease (NAFLD) is the most common liver disease worldwide. However, its molecular pathogenesis is incompletely characterized and clinical biomarkers remain scarce. The aims of these experiments were to identify and characterize liver protein alterations in an animal model of early, diet-related, liver injury and to assess novel candidate biomarkers in NAFLD patients. SN - 1477-5956 UR - https://doi.org/10.1186/s12953-018-0131-y DO - 10.1186/s12953-018-0131-y ID - Spanos2018 ER -