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Table 2 Enriched terms in proteins uniquely segregating with caveolae in gentamicin challenged cells. The 948 proteins uniquely segregating with caveolae in GTM treated cells where selected as the target group for the GOrilla enrichment analysis. The control dataset plus the GTM dataset were chosen as background group. GO terms with a FDR q-value p < 0.05 were considered in the table. “Molecular function” was the only in the GO category reaching significance. The majority of the proteins associated with the enriched terms are involved in protein kinases activity

From: In vitro gentamicin exposure alters caveolae protein profile in cochlear spiral ligament pericytes

Molecular function

GO term

Description

FDR q-value

Enrichment (N, B, n, b)

GO:0016772

transferase activity, transferring phosphorous-containing groups

6.34E-3

1.57 (2597.121, 932, 68)

GO:0016740

transferase activity

1.70E-2

1.32 (2597, 289, 932,137)

GO:0016773

phosphotransferase activity, alcohol group as acceptor

4.09E-2

1.60 (2597, 82, 932, 47)