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Fig. 1 | Proteome Science

Fig. 1

From: Effect of ovarian cancer ascites on SKOV-3 cells proteome: new proteins associated with aggressive phenotype in epithelial ovarian cancer

Fig. 1

Treatment of SKOV-3 cells with ascites from EOC patients. Cultures of SKOV-3 cell line were treated individually with five different ascites; Control, cells incubated in conventional culture medium with 10% of SFB used as reference for comparisons; A1 - A5, correspond to the five tested ascites. Black arrowhead indicates the presence of a large round cell with abundant cytoplasm; white arrowheads indicate membrane protrusions such as invadopodia, lamelipodia and filopodia present in cells treated with EOC ascites. General conditions of incubation for control and treatments were 72 h at 37 °C and 5 %CO2

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