Table 4 Gene Ontology (GO) enrichment analysis to classify down-regulated proteins

A). BIOLOGICAL PROCESSES

GOTERM

Immune response

0006955

Immune system process

0002376

Regulation of immune response

0050776

Defense response

006952

Positive regulation of immune response

0050778

Innate immune response

00450

Cell differentiation

003030154

Regulation of signaling

0023051

Cell morphogenesis

0000902

Negative regulation of cell communication

0010648

Response to stress

0006950

B). MOLECULAR FUNCTIONS

GOTERM

Enrichment for protein binding

0005515

Small molecule binding

0036094

Poli (A) RNA binding

0044822

Molecular regulator

0030234

Enzyme binding

00119899

C). CONSTITUENTS OF CELLULAR COMPONENTS

GOTERM

Extracellular exosomes

0070062

Membrane-bounded vesicle

0031988

Intracellular organelle lumen

0070013

Nucleoplasm

0005654

Golgi apparatus

0044431

Mitochondria

004429