Fig. 1
From: The interactome and proteomic responses of ALKBH7 in cell lines by in-depth proteomics analysis
Gene Ontology and pathway enrichment analysis of proteins enriched in mitochondrion associated with ALKBH7. (a) ALKBH7 complexes in the crude mitochondrial extract from HeLa S3 cells were enriched with anti-ALKBH7 agarose. Five regions of gel with distinctive protein bands were excised for in-gel digestion, and further identified by MS. (b) Gene Ontology and pathway enrichment analysis of identified proteins detected through IP-MS/MS. The categories of biological pathway, biological process, cellular component, and molecular function are shown in blue, red, green, and purple, respectively. The percentage of genes per category is represented by the size of the node. (c) Protein-protein interaction network constructed with enriched proteins in mitochondrion identified through IP-MS/MS