Fig. 4
From: The interactome and proteomic responses of ALKBH7 in cell lines by in-depth proteomics analysis
A comprehensive interaction network among the proteins changed in two biological TMT-MS/MS replicates. (a) Box plot denotes the fold change of DEPs in Cluster 3 and 5. Statistical outlier proteins are colored and labeled. (b) Protein-protein interaction network constructed with DEPs in two biological replicates of TMT-based MS/MS; no connective DEPs were excluded. DEPs are represented by colored nodes labeled with the gene name. The average fold changes of DEPs in two biological replicates of TMT-based MS/MS are reflected by color intensity. Upregulated and downregulated DEPs are shown in red and green, respectively. V-shape nodes denote DEPs located in mitochondrion. Node size correlates with the number of interactions