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Table 2 Identified proteins in samples extracted from CMD membrane (M), CSF (C) and dialysate (D)

From: Proteomic investigation of protein adsorption to cerebral microdialysis membranes in surgically treated intracerebral hemorrhage patients - a pilot study

Spot number

Accession number

Name of protein

Sequence covering (%)

Number of peptides

Theoretical pI/Mw

M1

P02766

Transthyretin

49.0

5

5.5/15887

M2

P02766

Transthyretin

39.5

3

5.5/15887

M3

P80511

Protein S100-A12

16.3

2

5.3/10575

M4

P02766

Transthyretin

48.3

4

5.5/15887

M5

P02766

Transthyretin

39.5

3

5.5/15887

M6

P02766

Transthyretin

39.5

3

5.5/15887

M7

P02766

Transthyretin

39.5

3

5.5/15887

M8#

119598216a

Calmodulin-like 4, isoform CRA c

30.0

3

5.9/13661

M9#

Q8WUW1

BRICK1

40.0

3

5.4/8745

M10#

O60220

Mitochondrial import inner membrane translocase subunit Tim8 A

64.9

3

5.1/10998

M11

P02766

Transthyretin

68.7

7

5.5/15887

M12

P02766

Transthyretin

48.3

4

5.5/15887

M13

P02766

Transthyretin

39.5

3

5.5/15887

M14

P00738

Haptoglobin alpha chain

17.5

4

5.6/15945

M15

P02671

Fibrinogen C-terminal

48.4

12

4.6/27292

M16

P02766

Transthyretin

63.9

5

5.5/15887

M17

P00738

Haptoglobin

32.5

9

6.3/276265

M18#

P06702

Protein S100-A9

57.9

6

5.7/13242

M 19#

E9NGZ5

Hemoglobin beta globin chain (Fragment)

93.3

7

5.9/11494

M20#

Q6V0K9

Mutant hemoglobin beta chain (Fragment)

94.3

8

6.2/11474

M21#

Q6V0K9

Mutant hemoglobin beta chain (Fragment)

76.2

6

6.2/11474

M22#

Q9BWU5

Mutant hemoglobin beta chain (Fragment)

45.7

4

6.5/11501

M23#

C9JKR2

Serum albumin (fragment)

19.7

6

6.0/47288

M24#

Q9BX83

Hemoglobin alpha 1 globin chain (Fragment)

52.0

4

7.1/10710

M25#

P52895

Aldo-keto reductase family 1 member C2

14.9

4

7.1/36736

C1

P02766

Transthyretin

49.0

5

5.5/15887

C2

P00738

Haptoglobin

32.8

10

6.3/276265

C3

P00738

Haptoglobin

30.8

11

6.3/276265

C4

P00738

Haptoglobin

30.6

9

6.3/276265

C5

P02766

Transthyretin

32.7

3

5.5/15887

C6

Q99497

Protein deglycase DJ-1

42.3

6

6.3/19891

C7

P01876

Ig alpha-1 chain C region

21.5

6

6.0/37654

C8

P09211

Glutathione S-transferase P

28.6

4

5.4/23356

C9

P09211

Glutathione S-transferase P

21.4

3

5.4/23356

C10

P32119

Peroxiredoxin-2

32.3

6

5.6/21892

C11

P02647

Apolipoprotein A-I

42.3

10

5.4/30777

C12

P02647

Apolipoprotein A-I

42.3

10

5.4/30777

C13

P02766

Transthyretin

63.9

6

5.5/15887

C14

P06702

Protein S100-A9

38.6

5

5.7/13242

C15

P06702

Protein S100-A9

56.1

6

5.7/13242

C16

P00738

Haptoglobin

14.3

3

6.3/276265

C17

P01009

Alpha-1-antitrypsin; Short peptide from AAT

9.6

3

5.3/46736

C18

P02766

Transthyretin

40.1

4

5.5/15887

C19

P00738

Haptoglobin

26.1

11

6.3/276265

C20

P00738

Haptoglobin

20.0

9

6.3/276265

C21

P02647

Apolipoprotein A-I

50.6

13

5.4/30777

C22

P01876

Ig alpha-1 chain C region

21.5

6

6.0/37654

C23

Q9NZT1

Calmodulin-like protein 5

9.6

2

4.3/15751

C24

P01009

Alpha-1-antitrypsin;Short peptide from AAT

10.3

6

5.3/46736

C25

P01040

Cystatin-A

36.7

4

5.4/11006

C26

P32119

Peroxiredoxin-2

26.8

5

5.6/21892

C27

P02647

Apolipoprotein A-I

67.0

18

5.4/30777

C28

P02647

Apolipoprotein A-I

59.2

15

5.4/30777

C29

P02647

Apolipoprotein A-I

18.0

5

5.4/30777

C30

P61769

Beta-2-microglobulin form pI 5.3.

16.8

2

5.3/11618

D1

P02766

Transthyretin

55.8

6

5.5/15887

D2

P02766

Transthyretin

55.1

5

5.5/15887

D3

P02766

Transthyretin

39.5

3

5.5/15887

D4

P02768

Albumin fragment

3.8

2

6.0/ 47,288

D5

P00738

Haptoglobin

6.4

3

6.3/276265

D6

P06702

Protein S100-A9

26.3

2

5.5/15887

D7

P01877

Ig alpha-2 chain C region (Ig like-2 domain)

10.2

3

6.1/10095

D8

P02768

Albumin fragment

28.9

15

6.0/ 47,288

D9

P00738

Haptoglobin

6.4

3

6.3/276265

D10

Q86YZ3

Hornerin fragment

6.4

4

4.8/9565

D11

Q86YZ3

Hornerin fragment

6.4

4

4.8/9565

D12

P61769

Beta-2-microglobulin

16.8

2

5.3/11618

D13

P81605

Dermcidin

10.0

1

6.1/ 11,283

D14

P68871

Hemoglobin subunit beta

43.5

3

6.8/ 15,867

D15

P68871

Hemoglobin subunit beta

47.5

2

6.8/ 15,867

D16

P69905

Hemoglobin subunit alpha

36.6

2

8.7/ 15,126

D17

P02768

Albumin fragment

10.0

3

6.0/ 47,288

D18

P81605

Dermcidin

20.0

2

6.1/ 11,283

D19

P00738

Haptoglobin

8.1

8

6.3/45200

D20

P00738

Haptoglobin

6.4

3

6.3/45200

D21

P02808

Statherin

54.8

1

8.0/7304

D22

P02768

Albumin fragment

11.3

7

6.0/ 47,288

D23

P02753

Retinol-binding protein 4

24.9

5

5.3/ 21,071

D24

P00738

Haptoglobin

6.2

2

6.3/45200

D25

P00738

Haptoglobin

6.2

2

6.3/45200

  1. Spot number refers to numbers in Fig. 5. Abbreviations: pI = isoelectric point; Mw = molecular mass. aindicates protein accession number according to NCBInr. Proteins were identified by MALDI-TOF (indicated by #) or LC-MS/MS (no #)