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Table 3 Demographic data for plasma samples used for targeted mass spectrometry biomarker validation

From: Analysis of plasma proteins using 2D gels and novel fluorescent probes: in search of blood based biomarkers for Alzheimer’s disease

 

Controls

Alzheimer Disease

P-value

Age in years

72.9 (6)

76.9 (7.4)

0.003*

% APOE ε4

13

37

0.01#

% APOE ε2

20.5

6.8

0.06#

% Female

50

50

 

Amyloid PET SUVR

1.17 (0.05)

2.35 (0.49)a

2e-10

n

44

44

 
  1. *p-value calculated using non-paired Student’s t-test
  2. #p-value for APOE allele frequency calculated using N-1 χ2
  3. aPET scans are only available for 22 of the 44 cases