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Fig. 3 | Proteome Science

Fig. 3

From: A risk score model based on TGF-β pathway-related genes predicts survival, tumor microenvironment and immunotherapy for liver hepatocellular carcinoma

Fig. 3

Gene mutation features and gene set enrichment analysis in TCGA-LIHC datasets. A-B Comparison of TMB (A) and number of mutated genes (B) between low- and high-risk groups. Student t test was conducted. C The waterfall diagram visualizing the top 10 mutated genes in the two risk groups (P < 0.05). Chi-square test was performed. D Enriched four KEGG pathways in low-risk group assessed by gene set enrichment analysis. TMB, tumor mutation burden. ES, enrichment score. NES, normalized enrichment score. FDR, false discovery rate. ns, no significance

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