Fig. 2

Identification and quantitative analysis of proteins. A The total identified proteins in MS analysis. The volcano plot showed the up-(red) or downregulated (blue) proteins between Model/Control groups (B) and JWDSD-H/Model groups (C) of 4549 proteins. D Venn diagram of different expression proteins and their overlap, the "+" indicates up-regulated proteins, while the "-" indicates down-regulated proteins, the "+ -" indicates proteins up-regulated in JWDSD-H/Model groups but down-regulated in Model/Control groups, the "- +" indicates proteins down-regulated in JWDSD-H/Model groups but up-regulated in Model/Control groups. Thresholds: up-regulated fold change ≥1.2, down-regulated fold change ≤ 0.83, Student t-test p-value < 0.05. E Hierarchical cluster analysis of 16 different expression proteins, the color indicates fold changes of proteins; deep purple indicates an increase while orange indicates a decrease.