Table 1 Top 20 changed DEPs in global proteomics
From: Proteomics profiling for the global and acetylated proteins of papillary thyroid cancers
| Â | Description | DEP | DEAP | ||
|---|---|---|---|---|---|
Ca-T vs Ca-N | p-value | Ca-T vs Ca-N | p-value | ||
Up-regulated | |||||
 1 | cDNA FLJ53365, highly similar to Homo sapiens fibronectin 1 (FN1) | 6.852 | 0.013391 | / | / |
 2 | Fibronectin 1 | 3.181 | 8.0355E-119 | 1.853 | 3.77348E-26 |
 3 | KRT1B protein | 2.912 | 0.002952313 | / | / |
 4 | Chitinase-3-like protein 1 | 2.666 | 0.003221145 | / | / |
 5 | Metalloproteinase inhibitor 1 | 2.23 | 0.007884891 | / | / |
 6 | Dermcidin | 2.209 | 0.007060387 | / | / |
 7 | Thrombospondin-2 | 2.151 | 0.020179382 | / | / |
 8 | Thrombospondin type-1 domain | 2.098 | 0.006753316 | / | / |
 9 | TNC protein | 1.926 | 2.51100E-16 | 1.319 | 0.013279683 |
 10 | cDNA FLJ59922, highly similar to Keratin, type II cytoskeletal 5 | 1.784 | 0.000395733 | / | / |
 11 | Collagen alpha-1(XII) chain | 1.779 | 0.000144431 | / | / |
 12 | Thrombospondin 1, isoform CRA_a | 1.777 | 8.63908E-07 | / | / |
 13 | Ferritin | 1.714 | 0.000459552 | / | / |
 14 | Adipocyte enhancer-binding protein 1 | 1.705 | 0.001401442 | / | / |
 15 | Ethylmalonic encephalopathy 1 isoform 3 | 1.699 | 0.001812266 | / | / |
 16 | cDNA FLJ25992 fis | 1.662 | 0.006486008 | / | / |
 17 | Periostin isoform thy6 | 1.643 | 2.87503E-11 | / | / |
 18 | Collagen, type XII | 1.631 | 0.011170308 | / | / |
 19 | Epididymis secretory sperm binding protein | 1.627 | 1.42457E-29 | 0.84 | 0.24960811 |
 20 | UDP-glucose 4-epimerase | 1.621 | 0.001662 | / | / |
Down-regulated | |||||
 1 | Adhesion G-protein-coupled receptor G1 | 0.48 | 0.019987729 | / | / |
 2 | cDNA FLJ53570, highly similar to Keratin, type I cytoskeletal 16 | 0.534 | 0.024382628 | / | / |
 3 | A-gamma globin Osilo variant | 0.535 | 2.444E-14 | / | / |
 4 | Huntingtin interacting protein-1 | 0.58 | 0.003860445 | / | / |
 5 | Ribosomal protein L19 | 0.585 | 0.049612805 | / | / |
 6 | cDNA, FLJ79193, highly similar to Beta-1,4-galactosyltransferase 1 | 0.593 | 0.000695376 | / | / |
 7 | Trefoil factor 3 | 0.621 | 9.53882E-08 | 0.406 | 0.010563374 |
 8 | UPF0764 protein | 0.623 | 0.008144689 | / | / |
 9 | Hemoglobin alpha-2 globin mutant | 0.638 | 8.85393E-08 | 0.728 | 0.268025154 |
 10 | Sulfotransferase | 0.639 | 0.000824192 | / | / |
 11 | 60S ribosomal protein L6 | 0.65 | 0.006101454 | / | / |
 12 | Sulfhydryl oxidase | 0.663 | 8.65178E-05 | / | / |
 13 | Carbonic anhydrase 1 | 0.67 | 5.56952E-27 | 0.65 | 5.44636E-06 |
 14 | Retinoid-inducible serine carboxypeptidase | 0.676 | 0.00147738 | / | / |
 15 | ER membrane protein complex subunit 1 | 0.68 | 0.019411598 | / | / |
 16 | Erythrocyte membrane protein band 4.2 | 0.687 | 0.022202241 | / | / |
 17 | Hemoglobin subunit alpha | 0.692 | 1.60939E-42 | 0.694 | 0.019044979 |
 18 | Creatine kinase B-type | 0.697 | 1.23955E-08 | 0.805 | 0.17691894 |
 19 | cDNA FLJ51076, weakly similar to LIM domain only protein 7 | 0.707 | 0.002702647 | / | / |
 20 | cDNA FLJ76704, highly similar to Homo sapiens leukemia inhibitory factor receptor (LIFR) | 0.71 | 0.018325546 | / | / |