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Table 3 KEGG pathways based on DEPs and DEAPs

From: Proteomics profiling for the global and acetylated proteins of papillary thyroid cancers

 

Pathway

P-value

Protein in Diff Exp

 

Protein in Background

Global proteomics

 1

Mineral absorption

0.000967

3

Cytochrome b reductase 1 (0.726), Metallothionein-2 (0.715), Ferritin light chain (1.612)

5

 2

Protein digestion and absorption

0.009736

3

Collagen alpha-1(III) chain (1.258), Collagen alpha-1(I) chain (1.247), Dipeptidyl peptidase 4 (1.547)

10

 3

Nicotinate and nicotinamide metabolism

0.020222

2

Purine nucleoside phosphorylase (1.27), Nicotinamide N-methyltransferase (1.402)

5

 4

Relaxin signaling pathway

0.036907

3

Collagen alpha-1(III) chain (1.258), Collagen alpha-1(I) chain (1.247), Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-12 (0.761)

16

Acetylated proteomics

 1

Proteoglycans in cancer

0.002704

3

Decorin (1.299), Lumican (1.22), Moesin (1.695)

4

 2

Viral carcinogenesis

0.011823

3

Histone H2B type 1-O (0.615), Complement C3 (1.221), 14-3-3 protein theta (1.215)

6

 3

Tight junction

0.04352

2

Moesin (1.695), Myosin regulatory light chain 12A (0.81)

4