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Table 4 The top 10 up- and down-regulated DEPs and DEAPs addressed in the literatures

From: Proteomics profiling for the global and acetylated proteins of papillary thyroid cancers

Proteomics

Change

Protein

Papillary thyroid carcinoma

Other cancers

Global

Up-regulated

Fibronectin 1

Y, increased [1]

Y, increased [2]

cDNA FLJ53365, highly similar to fibronectin 1, transcript variant 4

Y, increased

Y, increased

KRT1B protein

N

Y, increased [3]

Chitinase-3-like protein 1

Y, increased [4]

Y, increased [5]

Metalloproteinase inhibitor 1

Y, increased [6]

Y, increased [7]

Dermcidin

N

Y, increased [8]

Thrombospondin-2

Y, increased [9]

Y, increased [8]

Thrombospondin type 1

Y, increased [10]

Y, increased [11]

TNC protein

Y, increased [12]

Y, increased [13]

Keratin, type II cytoskeletal 5

N

Y, increased [14]

Down-regulated

Adhesion G-protein-coupled receptor G1

N

Y, [15]

Keratin, type I cytoskeletal 16

N

Y, [14]

A-gamma globin Osilo variant

N

N

Huntingtin interacting protein-1

N

Y, [16]

Ribosomal protein L19

N

Y, [17]

Beta-1,4-galactosyltransferase 1

N

Y, [18]

Trefoil factor 3

Y, decreased [19]

Y, decreased [20]

UPF0764 protein

N

N

Hemoglobin alpha-2 globin mutant

N

Y, [21]

Sulfotransferase

Y, [22]

Y, [23]

Acetylated

Up-regulated

Ribosomal protein L18a-like protein

N

N

Alpha-1-acid glycoprotein 2

N

Y, [24]

Eukaryotic peptide chain release factor GTP-binding subunit ERF3A

N

N

Glyoxalase domain-containing protein 4

N

N

Aminopeptidase B

N

N

Importin-7

N

N

Fibronectin 1

N

N

Calreticulin variant

N

N

Phosphatidylethanolamine-binding protein 1

N

N

Moesin

N

N

Down-regulated

Trefoil factor 3

N

N

Thyroglobulin

N

N

Histone H2B

N

Y, [25]

Uncharacterized protein DKFZp686G03277

N

N

Histone H2B type 1-O

N

N

Small nuclear ribonucleoprotein Sm D2

N

N

Carbonic anhydrase 1

N

N

Keratin, type II cytoskeletal 7

N

N

Liver histone H1e

N

N

Hemoglobin subunit alpha

N

N