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  1. Alfalfa (Medicago sativa) is the most extensively cultivated forage legume in the world, and salinity stress is the most problematic environmental factors limiting alfalfa production. To evaluate alfalfa tissue v...

    Authors: Junbo Xiong, Yan Sun, Qingchuan Yang, Hong Tian, Heshan Zhang, Yang Liu and Mingxin Chen
    Citation: Proteome Science 2017 15:19
    Content type: Research Published on:

  2. Changes in iron metabolism frequently accompany HIV-1 infection. However, while many clinical and in vitro studies report iron overload exacerbates the development of infection, many others have found no corre...

    Authors: Carmine Mancone, Alessio Grimaldi, Giulia Refolo, Isabella Abbate, Gabriella Rozera, Dario Benelli, Gian Maria Fimia, Vincenzo Barnaba, Marco Tripodi, Mauro Piacentini and Fabiola Ciccosanti
    Citation: Proteome Science 2017 15:18
    Content type: Research Published on:

  3. Identifying selective kinase inhibitors remains a major challenge. The design of bivalent inhibitors provides a rational strategy for accessing potent and selective inhibitors. While bivalent kinase inhibitors...

    Authors: Margaret L. Wong, Jason Murphy, Edmund Harrington, Carrie M. Gower, Rishi K. Jain, Markus Schirle and Jason R. Thomas
    Citation: Proteome Science 2017 15:17
    Content type: Research Published on:

  5. Determining small molecule—target protein interaction is essential for the chemical proteomics. One of the most important keys to explore biological system in chemical proteomics field is finding first-class m...

    Authors: Kyungtae Kang, Jongmin Park and Eunha Kim
    Citation: Proteome Science 2017 15:15
    Content type: Review Published on:

  6. Protein-protein interactions (PPIs) trigger a wide range of biological signaling pathways that are crucial for biomedical research and drug discovery. Various techniques have been used to study specific protei...

    Authors: Dhiraj P. Murale, Seong Cheol Hong, Md. Mamunul Haque and Jun-Seok Lee
    Citation: Proteome Science 2017 15:14
    Content type: Review Published on:

  8. Liver models that closely mimic the in vivo microenvironment are useful for understanding liver functions, capabilities, and intercellular communication processes. Three-dimensional (3D) liver models assembled...

    Authors: Lucas T. Vu, Sophia M. Orbach, W. Keith Ray, Margaret E. Cassin, Padmavathy Rajagopalan and Richard F. Helm
    Citation: Proteome Science 2017 15:12
    Content type: Research Published on:

  9. Unlike humans, there is currently no publicly available reference mass spectrometry-based circulating acellular proteome data for sheep, limiting the analysis and interpretation of a range of physiological cha...

    Authors: Saul Chemonges, Rajesh Gupta, Paul C. Mills, Steven R. Kopp and Pawel Sadowski
    Citation: Proteome Science 2017 15:11
    Content type: Research Published on:

  11. Drought (Water deficit, WD) poses a serious threat to extensively economic losses of trees throughout the world. Chinese dwarf cherry (Cerasus humilis) is a good perennial plant for studying the physiological and...

    Authors: Zepeng Yin, Jing Ren, Lijuan Zhou, Lina Sun, Jiewan Wang, Yulong Liu and Xingshun Song
    Citation: Proteome Science 2017 15:9
    Content type: Research Published on:

  12. Data from biological samples and medical evaluations plays an essential part in clinical decision making. This data is equally important in clinical studies and it is critical to have an infrastructure that en...

    Authors: Jonatan Eriksson, Simone Andersson, Roger Appelqvist, Elisabet Wieslander, Mikael Truedsson, May Bugge, Johan Malm, Magnus Dahlbäck, Bo Andersson, Thomas E. Fehniger and György Marko-Varga
    Citation: Proteome Science 2017 15:8
    Content type: Research Published on:

  13. Hepatitis B virus (HBV) is a global health problem, and infected patients if left untreated may develop cirrhosis and eventually hepatocellular carcinoma. This study aims to enlighten pathways associated with ...

    Authors: Seyma Katrinli, Kamil Ozdil, Abdurrahman Sahin, Oguzhan Ozturk, Gozde Kir, Ahmet Tarik Baykal, Emel Akgun, Omer Sinan Sarac, Mehmet Sokmen, H. Levent Doğanay and Gizem Dinler Doğanay
    Citation: Proteome Science 2017 15:7
    Content type: Research Published on:

  14. Reactive oxygen species (ROS) production is an early event in the immune response of plants. ROS production affects the redox-based modification of cysteine residues in redox proteins, which contribute to prot...

    Authors: Kazuko Morino, Mayumi Kimizu and Masayuki Fujiwara
    Citation: Proteome Science 2017 15:6
    Content type: Research Published on:

  15. Malaria continues to be a great public health concern due to the significant mortality and morbidity associated with the disease especially in developing countries. Microparticles (MPs), also called plasma mem...

    Authors: Samuel Antwi-Baffour, Jonathan Kofi Adjei, Francis Agyemang-Yeboah, Max Annani-Akollor, Ransford Kyeremeh, George Awuku Asare and Ben Gyan
    Citation: Proteome Science 2017 15:5
    Content type: Research Published on:

  16. Eggshells which consist largely of calcareous outer shell and shell membranes, constitute a significant part of poultry hatchery waste. The shell membranes (ESM) not only contain proteins that originate from e...

    Authors: N. C. Rath, R. Liyanage, S. K. Makkar and J. O. Lay Jr.
    Citation: Proteome Science 2017 15:4
    Content type: Research Published on:

  17. Non-starch polysaccharide enzymes (NSPEs) have long been used in monogastric animal feed production to degrade non-starch polysaccharides (NSPs) to oligosaccharides in order to promote growth performance and g...

    Authors: Jize Zhang, Yang Gao, Qingping Lu, Renna Sa and Hongfu Zhang
    Citation: Proteome Science 2017 15:3
    Content type: Research Published on:

  18. The degradation of the steppe of Inner Mongolia, due to overgrazing, has resulted in ecosystem damage as well as extensive reductions in sheep production. The growth performance of sheep is greatly reduced bec...

    Authors: Weibo Ren, Xiangyang Hou, Yuqing Wang, Warwick Badgery, Xiliang Li, Yong Ding, Huiqin Guo, Zinian Wu, Ningning Hu, Lingqi Kong, Chun Chang, Chao Jiang and Jize Zhang
    Citation: Proteome Science 2017 15:2
    Content type: Research Published on:

  20. Proteomic matrix-assisted laser desorption/ionisation (MALDI) linear time-of-flight (TOF) mass spectrometry (MS) may be used to produce protein profiles from biological samples with the aim of discovering biom...

    Authors: Tyman E. Stanford, Christopher J. Bagley and Patty J. Solomon
    Citation: Proteome Science 2016 14:19
    Content type: Methodology Published on:

  21. Myoglobin (Mb) is a sarcoplasmic heme protein primarily responsible for meat color and its chemistry is species specific. 4-hydroxy-2-nonenal (HNE) is a cytotoxic lipid derived aldehyde detected in meat and wa...

    Authors: Naveena B. Maheswarappa, K. Usha Rani, Y. Praveen Kumar, Vinayak V. Kulkarni and Srikanth Rapole
    Citation: Proteome Science 2016 14:18
    Content type: Research Published on:

  22. Human follicular fluid (FF) is a unique biological fluid in which the oocyte develops in vivo, and presents an optimal source for non-invasive biochemical predictors. Oocyte quality directly influences the emb...

    Authors: Fang Chen, Carl Spiessens, Thomas D’Hooghe, Karen Peeraer and Sebastien Carpentier
    Citation: Proteome Science 2016 14:17
    Content type: Research Published on:

  23. Daurian ground squirrels (Spermophilus dauricus) deviate from significant increase of protein catabolism and loss of myofibrillar contents during long period of hibernation inactivity.

    Authors: Hui Chang, Shan-Feng Jiang, Kai Dang, Hui-Ping Wang, Shen-Hui Xu and Yun-Fang Gao
    Citation: Proteome Science 2016 14:16
    Content type: Research Published on:

  24. The acquisition of iron is important for the pathogenicity of bacteria and blood. Three different culture environments (Fe stimulation, blood agar plate and normal plate) were used to stimulate Enterobacter cloac...

    Authors: Dijun Zhang, Weina He, Qianqian Tong, Jun Zhou and Xiurong Su
    Citation: Proteome Science 2016 14:15
    Content type: Research Published on:

  26. Plenty of proteomic studies were performed to characterize the allotetraploid upland cotton fiber elongation process, whereas little is known about the elongating diploid cotton fiber proteome.

    Authors: Bing Zhang, Shao-Jun Du, Jue Hu, Di Miao and Jin-Yuan Liu
    Citation: Proteome Science 2016 14:13
    Content type: Research Published on:

  28. Metal-organic frameworks (MOFs - MIL-101) are the most exciting, high profiled developments in nanotechnology in the last ten years, and it attracted considerable attention owing to their uniform nanoporosity,...

    Authors: Soundharrajan Ilavenil, Naif Abdullah Al-Dhabi, Srisesharam Srigopalram, Young Ock Kim, Paul Agastian, Rajasekhar Baaru, Ki Choon Choi, Mariadhas Valan Arasu, Chun Geon Park and Kyung Hun Park
    Citation: Proteome Science 2016 14:11
    Content type: Research Published on:

  29. Cervical cancer (CC) is the fourth most common cancer in women worldwide with an estimated 528,000 new cases in 2012. The same year México had an incidence of 13,960 and a mortality of 4769 cases. There are se...

    Authors: Idanya Serafín-Higuera, Olga Lilia Garibay-Cerdenares, Berenice Illades-Aguiar, Eugenia Flores-Alfaro, Marco Antonio Jiménez-López, Pavel Sierra-Martínez and Luz del Carmen Alarcón-Romero
    Citation: Proteome Science 2016 14:10
    Content type: Research Published on:

  31. RAW 264.7 cells can differentiate into osteoclasts when cultured in medium supplemented with 1 % FBS. However, the proteomic changes in the development of RAW 264.7 cells into osteoclasts in low serum culture ...

    Authors: Qi Xiong, Lihai Zhang, Shaohua Zhan, Wei Ge and Peifu Tang
    Citation: Proteome Science 2016 14:8
    Content type: Research Published on:

  32. Cystatin C (CysC) is an endogenous cysteine protease inhibitor that can be used to assess the progression of kidney function. Recent studies demonstrate that CysC is a more specific indicator of glomerular fil...

    Authors: Hussein N. Yassine, Olgica Trenchevska, Zhiwei Dong, Yara Bashawri, Juraj Koska, Peter D. Reaven, Randall W. Nelson and Dobrin Nedelkov
    Citation: Proteome Science 2016 14:7
    Content type: Research Published on:

  33. Maternal Embryonic Leucine Zipper Kinase (MELK) is a serine/threonine kinase involved in cell cycle, differentiation, proliferation, and apoptosis. These multiple features are consistent with it being a potent...

    Authors: Suely Kazue Nagahashi Marie, Sueli Mieko Oba-Shinjo, Roseli da Silva, Marcela Gimenez, Gisele Nunes Reis, Jean-Pierre Tassan, Jose Cesar Rosa and Miyuki Uno
    Citation: Proteome Science 2016 14:6
    Content type: Research Published on:

  34. The cellular immune response for Mycobacterium tuberculosis (M. tuberculosis) infection remained incompletely understood. To uncover membrane proteins involved in this infection mechanism, an integrated approach ...

    Authors: Chiu-Ping Kuo, Kuo-Song Chang, Jue-Liang Hsu, I-Fang Tsai, Andrew Boyd Lin, Tsai-Yin Wei, Chien-Liang Wu and Yen-Ta Lu
    Citation: Proteome Science 2016 14:5
    Content type: Research Published on:

  35. Kidney stone matrix protein composition is an important yet poorly understood aspect of nephrolithiasis. We hypothesized that this proteome is considerably more complex than previous reports have indicated and...

    Authors: Frank A. Witzmann, Andrew P. Evan, Fredric L. Coe, Elaine M. Worcester, James E. Lingeman and James C. Williams Jr
    Citation: Proteome Science 2016 14:4
    Content type: Methodology Published on:

  37. Rice bacterial blight (BB) caused by Xanthomonas oryzae pv.oryzae (Xoo) is one of the most devastating bacterial diseases in rice-growing regions worldwide. The rice-Xoo interaction is a classical model for study...

    Authors: Xian Chen, Zhiping Deng, Chulang Yu, Chengqi Yan and Jianping Chen
    Citation: Proteome Science 2016 14:2
    Content type: Research Published on:

  38. Snake venom is a source of many pharmacologically important molecules. Agkistrodon bilineatus commonly known as Cantil, is spread over Central America particularly in Mexico and Costa Rica. From the venom of Agki...

    Authors: Aisha Munawar, Anum Zahid, Amr Negm, Ahmed Akrem, Patrick Spencer and Christian Betzel
    Citation: Proteome Science 2016 14:1
    Content type: Research Published on:

  39. The periodontal disease is caused by a set of inflammatory disorders characterized by periodontal pocket formation that lead to tooth loss if untreated. The proteomic profile and related molecular conditions o...

    Authors: Emanuela Monari, Aurora Cuoghi, Elisa Bellei, Stefania Bergamini, Andrea Lucchi, Aldo Tomasi, Pierpaolo Cortellini, Davide Zaffe and Carlo Bertoldi
    Citation: Proteome Science 2015 13:33
    Content type: Research Published on:

  40. Intrauterine growth restriction (IUGR) may program metabolic alterations affecting physiological functions and lead to diseases in later life. The adipose tissue is an important organ influencing energy homeos...

    Authors: Adriana Pereira de Souza, Amanda Paula Pedroso, Regina Lúcia Harumi Watanabe, Ana Paula Segantine Dornellas, Valter Tadeu Boldarine, Helen Julie Laure, Claudia Maria Oller do Nascimento, Lila Missae Oyama, José Cesar Rosa and Eliane Beraldi Ribeiro
    Citation: Proteome Science 2015 13:32
    Content type: Research Published on:

  41. It has been discussed if the adverse health effect associated with the ingestion of trans fatty acids correlates with the food source, as the composition of the isomers varies in different foods. We have investig...

    Authors: Toke P. Krogager, Lone Vendel Nielsen, Derya Kahveci, Thomas F. Dyrlund, Carsten Scavenius, Kristian W. Sanggaard and Jan J. Enghild
    Citation: Proteome Science 2015 13:31
    Content type: Research Published on:

  42. Membrane microdomains represent dynamic membrane nano-assemblies enriched in signaling molecules suggesting their active involvement in not only physiological but also pathological molecular processes. The hyp...

    Authors: Viorel-Iulian Suica, Elena Uyy, Raluca Maria Boteanu, Luminita Ivan and Felicia Antohe
    Citation: Proteome Science 2015 13:30
    Content type: Research Published on:

  44. The oil palm Elaeis guineensis Jacq. which produces the highest yield per unit land area of the oil crops is the most important commercial oil crop in South East Asia. The fleshy mesocarp of oil palm fruit, where...

    Authors: Tony Eng Keong Ooi, Wan Chin Yeap, Leona Daniela Jeffery Daim, Boon Zean Ng, Fong Chin Lee, Ainul Masni Othman, David Ross Appleton, Fook Tim Chew and Harikrishna Kulaveerasingam
    Citation: Proteome Science 2015 13:28
    Content type: Research Published on:

  46. The harmful consequences of in utero irradiation on learning and memory have been recognised but the molecular mechanisms behind the damage are still unknown.

    Authors: Stefan J. Kempf, Christine von Toerne, Stefanie M. Hauck, Michael J. Atkinson, Mohammed A. Benotmane and Soile Tapio
    Citation: Proteome Science 2015 13:26
    Content type: Research Published on:

  47. Bats are recognised as an important reservoir for a number of highly pathogenic zoonotic viruses. While many of these viruses cause severe and often fatal disease in humans, bats are able to coexist with these...

    Authors: Lawrence Mok, James W. Wynne, Kris Ford, Brian Shiell, Antony Bacic and Wojtek P. Michalski
    Citation: Proteome Science 2015 13:25
    Content type: Research Published on:

  48. Histones and their post-translational modifications impact cellular function by acting as key regulators in the maintenance and remodeling of chromatin, thus affecting transcription regulation either positivel...

    Authors: Pawel Olszowy, Maire Rose Donnelly, Chanho Lee and Pawel Ciborowski
    Citation: Proteome Science 2015 13:24
    Content type: Research Published on:

  49. Protein immunoprecipitation (IP) coupled with MS provides means to interrogate protein complexes and their posttranslational modifications (PTMs). In a typical protein IP assay antibodies are conjugated to pro...

    Authors: Michal Mikula, Tymon Rubel, Jakub Karczmarski, Malgorzata Statkiewicz, Karol Bomsztyk and Jerzy Ostrowski
    Citation: Proteome Science 2015 13:23
    Content type: Methodology Published on:
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