Skip to main content

Advertisement

Table 2 Part of the identified proteins that may be interesting in potential biomarker discovery of early ischemia in myocardium

From: Proteomic analysis of effluents from perfused human heart for transplantation: identification of potential biomarkers for ischemic heart damage

Protein name Function Distinct peptide MW(Da) Organ specific Clinical marker
Isoform M1 of Pyruvate kinase isozymes M1/M2 metabolism 12 58,062.4 yes yes
Actin, alpha cardiac muscle 1 cytoskeleton 8 42,019.2 yes  
Aspartate aminotransferase 1 metabolism (amino acid) 6 46,247.7   yes
Creatine kinase M-type energ transduction 15 43,101.4 yes yes
Heart -fatty acid-binding protein, lipid transport 9 14,858.1 yes yes
Glyceraldehyde-3-phosphate dehydrogenase metabolism (glycolysis) 14 36,053.4   
L-lactate dehydrogenase B chain metabolism (glycolysis) 14 36,638.7 yes yes
Myoglobin oxygen transport 17 17,183.9 yes yes
Isoform 1 of Triosephosphate isomerase metabolism (glycolysis) 12 30,791.2   
Isoform 8 of Titin cytoskeletal activity 4 3829,893.5 yes  
Glucose-6-phosphate isomerase metabolism (glycolysis) 5 63147.5   
Isoform 1 of Gelsolin cytoskeletal activity 9 85697.9   
Phosphoglycerate mutase 2 metabolism (glycolysis) 2 28766.3 yes  
Adipocyte -fatty acid-binding protein lipid transport 9 14719   
Adenylate kinase 1 ATP regeneration 5 23410.9   
Creatine kinase B-type kinase activity 2 42644.5   
Four and a half LIM domains 1 variant protein binding 5 33578.9   
Malate dehydrogenase, cytoplasmic metabolism (glycolysis) 12 36426.3   
Phosphatidylethanolamine-binding protein 1 protease inhibitor 8 21056.9   
PGM1 65 kDa protein magnesium ion binding 3 64560.9   
Superoxide dismutase oxidoreductase 1 15935.8