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  1. Lumbrokinase derived from earthworms, Lumbricus rubellus is known to have fibrinolytic enzymes that have potential as therapeutic drugs due to its ability to dissolve fibrin. The current study is aimed to purify ...

    Authors: Laurentia Stephani, Puji Rahayu, Debbie Retnoningrum, Maggy Thenawidjaja Suhartono, Heni Rachmawati and Raymond R. Tjandrawinata
    Citation: Proteome Science 2023 21:8
    Content type: Research Published on:

  2. We investigated differentially expressed proteins (DEPs) in human glioblastoma U87 cells after treatment with hederagenin as a therapeutic screening mechanism and provided a theoretical basis for hederagenin i...

    Authors: Yesen Zhang, Yi Han, Yuchun Shang, Xiangyu Wang and Jiwei Sun
    Citation: Proteome Science 2023 21:7
    Content type: Research Published on:

  3. Papillary thyroid carcinoma (PTC) is the most common endocrine malignancy cancer among the malignancies of thyroid. Despite of wide usages of proteomics in PTC, the profile of acetylated proteins in PTC remain...

    Authors: Wei Wei, Yuezhang Wu, Dong-Dong Chen, Yuntao Song, Guohui Xu, Qi Shi and Xiao-Ping Dong
    Citation: Proteome Science 2023 21:6
    Content type: Research Published on:

  4. This study aims to explore the effect of an extract of Atractylodes lancea (A. lancea) on antibiotics-induced intestinal tract disorder and the probable therapeutic mechanisms employed by this extract to ameliora...

    Authors: BaiNian Zhang, Lan Bu, Hui Tian, ZhangQiang You, MingHai Zhao, Jie Tian, YuanYuan Zhang, Qian Wang, ChengJia Tan, Yu Cao, DaRen Feng and ZhenPeng Xi
    Citation: Proteome Science 2023 21:5
    Content type: Research Published on:

  5. Macrophages have a vital role in phagocytosis and antiviral effect against invading influenza viruses. Previously, we found that methionine enkephalin (MENK) inhibited influenza virus infection by upregulating...

    Authors: Wenrui Fu, Zifeng Xie, Mei Bai, Zhen Zhang, Yuanlong Zhao and Jing Tian
    Citation: Proteome Science 2023 21:4
    Content type: Research Published on:

  6. Exosomes in the body fluid are effective cell-derived membranous structures transferring various molecules to mediate intercellular communication. The expression of protein in the urinary exosomes from the col...

    Authors: Ling Ma, Haijiao Yu, Yubing Zhu, Kaiyu Xu, Aimin Zhao, Lei Ding, Hong Gao and Man Zhang
    Citation: Proteome Science 2023 21:3
    Content type: Research Published on:

  7. This study aims to decode the proteomic signature of cardiomyocytes in response to lncRNA Ftx knockdown and overexpression via proteomic analysis, and to study the biological role of lncRNA Ftx in cardiomyocyt...

    Authors: Xiangfei Sun, Ying Jiang, Qingbao Li, Qi Tan, Mingliang Dong, Bi’e Cai, Di Zhang and Qi Zhao
    Citation: Proteome Science 2023 21:2
    Content type: Research Published on:

  8. Dl-3-n-butylphthalide (NBP) is an important medial therapy for acute ischemic stroke in China. Recent studied have revealed that NBP not only rescued the loss of dopaminergic neurons in cellular and animal mod...

    Authors: Yuan Zhao, Jian Zhang, Yidan Zhang, Shuyue Li, Ya Gao, Cui Chang, Xiang Liu, Lei Xu and Guofeng Yang
    Citation: Proteome Science 2023 21:1
    Content type: Research Published on:

  9. Horticulture productivity has been increasingly restricted by heat stress from growing global warming, making it far below the optimum production capacity. As a popular ornamental cultivar of tree peony, Paeonia ...

    Authors: Jin Ma, Qun Wang, Ling-Ling Wei, Yu Zhao, Guo-Zhe Zhang, Jie Wang and Cui-Hua Gu
    Citation: Proteome Science 2022 20:18
    Content type: Research Published on:

  10. Every year, approximately 17 million people worldwide die due to coronary heart disease, with China ranking second in terms of the death toll. Myocardial ischemia-reperfusion injury (MIRI) significantly influe...

    Authors: Xiang-Mei Zhu, Yang Tan, Yu-He Shi, Qing Li, Jue Zhu, Xiang-Dan Liu and Qiao-Zhen Tong
    Citation: Proteome Science 2022 20:17
    Content type: Research Published on:

  11. Hypoxia is a risk factor for non-alcoholic fatty liver diseases, leading to permanent imbalance of liver lipid homeostasis and steatohepatitis. However, a detailed understanding of the metabolic genes and path...

    Authors: Jin Xu, Wen-jie Chen, Zhan Wang, Ming-yuan Xin, Shen-han Gao, Wen-jing Liu, Kai-kun Wang, Jing-wei Ma, Xin-zong Yan and Yan-ming Ren
    Citation: Proteome Science 2022 20:16
    Content type: Research Published on:

  12. Multi-omics technology provides a good tool to analyze the protein toxin composition and search for the potential pathogenic factors of Solenopsis invicta, under the great harm of the accelerated invasion in sout...

    Authors: Liuyang Cai, Fengling Yang, Yongfang Wang, Jishun Yang, Yina Zhu, Xueqi Ma, Juan Höfer, Yichao Wang, Yajun Ma and Liang Xiao
    Citation: Proteome Science 2022 20:15
    Content type: Research Published on:

  13. Citrate Synthase (Cs) gene mutation (locus ahL4) has been found to play an important role in progressive hearing loss of A/J mice. HEI-OC1 cells have been widely used as an in vitro system to study cellular and m...

    Authors: Xiaowen Xu, Yue Liu, Jun Luan, Rongrong Liu, Yan Wang, Yingying Liu, Ang Xu, Bingxin Zhou, Fengchan Han and Wenjing Shang
    Citation: Proteome Science 2022 20:14
    Content type: Research Published on:

  14. Understanding the molecular and cellular mechanisms involved in the pathogenesis of ocular injured induced by mustard gas can help better identify complications and discover appropriate therapies. This study a...

    Authors: Shahram Parvin, Alireza Shahriary, Hossein Aghamollaei, B. Fatemeh Nobakht M. Gh, Hasan Bagheri, Mostafa Ghanei, Seyed-Hashem Daryabari, Khosrow Jadidi and Masoud Arabfard
    Citation: Proteome Science 2022 20:13
    Content type: Research Published on:

  15. Aging is a complex biological process accompanied by a time-dependent functional decline that affects most living organisms. Omics studies help to comprehensively understand the mechanism of aging and discover...

    Authors: Jiang-Feng Liu, Yue Wu, Ye-Hong Yang, Song-Feng Wu, Shu Liu, Ping Xu and Jun-Tao Yang
    Citation: Proteome Science 2022 20:12
    Content type: Research Published on:

  16. Transforming growth factor-beta (TGF-β) signal is an important pathway involved in all stages of liver hepatocellular carcinoma (LIHC) initiation and progression. Therefore, targeting TGF- β pathway may be a p...

    Authors: Jingsheng Liao, Qi Liu, Jingtang Chen, Zhibin Lu, Huiting Mo and Jun Jia
    Citation: Proteome Science 2022 20:11
    Content type: Research Published on:

  17. Acute respiratory distress syndrome (ARDS) is characterized by refractory hypoxemia caused by accumulation of pulmonary fluid, which is related to inflammatory cell infiltration, impaired tight junction of pul...

    Authors: Xu-Peng Wen, Guo Long, Yue-Zhong Zhang, He Huang, Tao-Hua Liu and Qi-Quan Wan
    Citation: Proteome Science 2022 20:10
    Content type: Research Published on:

  18. The epidermal growth factor receptor (EGFR) overexpression is found in metastatic colorectal cancer (mCRC). Targeted molecular therapies such as monoclonal antibodies (mAbs) and tyrosine kinase inhibitors (TKI...

    Authors: Thomanai Lamtha, Sucheewin Krobthong, Yodying Yingchutrakul, Pawitrabhorn Samutrtai, Christopher Gerner, Lueacha Tabtimmai and Kiattawee Choowongkomon
    Citation: Proteome Science 2022 20:9
    Content type: Research Published on:

  19. Bacterial meningitis (BM) is a life-threatening infectious disease of the central nervous system in infants and children. To date, no diagnostic methods for the early and precise diagnosis of paediatric BM hav...

    Authors: Ting Luo, Sai Yang, Yan Chen, Shulei Liu, Liming Yang, Nanfei Hu, Ye Ma, Jun Qiu, Kewei Wang, Liping Li and Lihong Tan
    Citation: Proteome Science 2022 20:8
    Content type: Research Published on:

  22. The surveillance and therapy of early-stage cancer would be better for patients’ prognosis. However, the extreme trace amount of tissue samples in different stages have limited in portraying the characterizati...

    Authors: Lingling Li, Hui Liu, Yan Li, Chunmei Guo, Bing Wang, Dan Shen, Qiao Zhang and Chen Ding
    Citation: Proteome Science 2022 20:5
    Content type: Research Published on:

  23. The pathogen of banana Fusarium oxysporum f. sp. cubense race 4(Foc4) infects almost all banana species, and it is the most destructive. The molecular mechanism of the interactions between Fusarium oxysporum and ...

    Authors: Hui Fang, Cheng Zhong and Chunyan Tang
    Citation: Proteome Science 2022 20:4
    Content type: Research Published on:

  24. B-cell acute lymphoblastic leukemia (B-ALL) is the most common malignancy of childhood. Even though significant progresses have been made in the treatment of B-ALL, some pediatric B-ALL have still poor prognos...

    Authors: Runhong Yu, Shiwei Yang, Yufeng Liu and Zunmin Zhu
    Citation: Proteome Science 2022 20:3
    Content type: Research Published on:

  25. The Australian Imaging and Biomarker Lifestyle (AIBL) study of aging is designed to aid the discovery of biomarkers. The current study aimed to discover differentially expressed plasma proteins that could yiel...

    Authors: Scott B. Laffoon, James D. Doecke, Anne M. Roberts, Jennifer A. Vance, Benjamin D. Reeves, Kelly K. Pertile, Rebecca L. Rumble, Chris J. Fowler, Brett Trounson, David Ames, Ralph Martins, Ashley I. Bush, Colin L. Masters, Paul A. Grieco, Edward A. Dratz and Blaine R. Roberts
    Citation: Proteome Science 2022 20:2
    Content type: Research Published on:

  26. Cardiovascular diseases remain the leading cause of morbidity and mortality worldwide, most of which are caused by atherosclerosis. Discerning processes that participate in macrophage-to-foam cell formation ar...

    Authors: Yali Zhang, Yu Fu, Linying Jia, Chenyang Zhang, Wenbin Cao, Naqash Alam, Rong Wang, Weirong Wang, Liang Bai, Sihai Zhao and Enqi Liu
    Citation: Proteome Science 2022 20:1
    Content type: Research Published on:

  27. Streptococcus agalactiae is a common colonizer of the rectovaginal tract and lead to infectious diseases of neonatal and non-pregnant adults, which also causes infectious disease in fish and a zoonotic risk as w...

    Authors: Xinjin Chen, Bolin Fan, Chenlong Fan, Zhongliang Wang, Eakapol Wangkahart, Yucong Huang, Yu Huang, Jichang Jian and Bei Wang
    Citation: Proteome Science 2021 19:14
    Content type: Research Published on:

  29. Gout is a common and complex form of immunoreactive arthritis based on hyperuricemia, while the symptoms would turn to remission or even got worse. So, it is hard to early identify whether an asymptomatic hype...

    Authors: Guangqi Chen, Jiafen Cheng, Hanjie Yu, Xiao Huang, Hui Bao, Ling Qin, Ling Wang, Yaxiang Song, Xinying Liu and Ai Peng
    Citation: Proteome Science 2021 19:12
    Content type: Research Published on:

  30. The target-decoy strategy effectively estimates the false-discovery rate (FDR) by creating a decoy database with a size identical to that of the target database. Decoy databases are created by various methods,...

    Authors: Sangjeong Lee, Heejin Park and Hyunwoo Kim
    Citation: Proteome Science 2021 19:11
    Content type: Research Published on:

  32. Tibetan pigs (TP) exhibit heritable adaptations to their hypoxic environments as a result of natural selection. However, candidate proteins that affect the sperm quality of boars on plateaus have not yet been ...

    Authors: Yanling Zhao, Yaomei Wang, Feipeng Guo, Bo Lu, Jiale Sun, Jianzhou Wang and Zili Ren
    Citation: Proteome Science 2021 19:9
    Content type: Research Published on:

  33. Kiwifruit (Actinidia chinensis var. Chinensis) is abundant with vitamin C and is a rapidly developing crop in China, New Zealand, and other countries. It has been widely used as a raw material for food and kiwifr...

    Authors: Yu Zhang, Yuexing Wang, Wanying Zhou, Shimao Zheng and Wenhui Zhang
    Citation: Proteome Science 2021 19:8
    Content type: Research Published on:

  34. The black soldier fly (Hermetia illucens) has significant economic potential. The larvae can be used in financially viable waste management systems, as they are voracious feeders able to efficiently convert low-q...

    Authors: Yu-Bo Lin, Jing-Jing Rong, Xun-Fan Wei, Zhuo-Xiao Sui, Jinhua Xiao and Da-Wei Huang
    Citation: Proteome Science 2021 19:7
    Content type: Research Published on:

  35. Spotted stem borer- Chilo partellus - a Lepidopteran insect pest of Sorghum bicolor is responsible for major economic losses. It is an oligophagous pest, which bores through the plant stem, causing ‘deadheart’ an...

    Authors: Vaijayanti A. Tamhane, Surhud S. Sant, Abhilash R. Jadhav, Abdul R. War, Hari C. Sharma, Abdul Jaleel and Akanksha S. Kashikar
    Citation: Proteome Science 2021 19:6
    Content type: Research Published on:

  37. Escherichia coli (E. coli) is the principal pathogen that causes biofilm formation. Biofilms are associated with infectious diseases and antibiotic resistance. This study employed proteomic analysis to identify d...

    Authors: Huiyi Song, Ni Lou, Jianjun Liu, Hong Xiang and Dong Shang
    Citation: Proteome Science 2021 19:4
    Content type: Research Published on:

  38. Preterm birth (PTB) is one of major causes of perinatal mortality and neonatal morbidity, but knowledge of its complex etiology is still limited. Here we present cervicovaginal fluid (CVF) protein profiles of ...

    Authors: Young Eun Kim, Kwonseong Kim, Han Bin Oh, Sung Ki Lee and Dukjin Kang
    Citation: Proteome Science 2021 19:3
    Content type: Research Published on:

  39. Apple replant disease (ARD) has been reported from all major fruit-growing regions of the world, and is often caused by biotic factors (pathogen fungi) and abiotic factors (phenolic compounds). In order to cla...

    Authors: Rong Zhang, Weitao Jiang, Xin Liu, Yanan Duan, Li Xiang, Yanfang Wang, Yuanmao Jiang, Xiang Shen, Xuesen Chen, Chengmiao Yin and Zhiquan Mao
    Citation: Proteome Science 2021 19:2
    Content type: Research Published on:

  40. Protein lysine malonylation, a novel post-translational modification (PTM), has been recently linked with energy metabolism in bacteria. Staphylococcus aureus is the third most important foodborne pathogen worldw...

    Authors: Yanan Shi, Jingjing Zhu, Yan Xu, Xiaozhao Tang, Zushun Yang and Aixiang Huang
    Citation: Proteome Science 2021 19:1
    Content type: Research Published on:

  41. Stemazole is a novel small molecule that has been suggested to have the ability to protect multiple stem cells. The proliferation-promoting activity and promising neuroprotective effects of stemazole make it a...

    Authors: Huajun Li, Yubo Zhang, Jing Zhang, Chaoran Zhao, Yizi Zhu and Mei Han
    Citation: Proteome Science 2020 18:12
    Content type: Research Published on:

  43. Tuberculosis (TB) is one of the world’s most problematic infectious diseases. The pathogen Mycobacterium tuberculosis (Mtb) is contained by the immune system in people with latent TB infection (LTBI). No overt di...

    Authors: Takele Teklu, Biniam Wondale, Biruhalem Taye, Milkessa Hailemariam, Shiferaw Bekele, Mesfin Tamirat, Aboma Zewude, Temesgen Mohamed, Girmay Medhin, Mengistu Legesse, Yanbao Yu, Gobena Ameni and Rembert Pieper
    Citation: Proteome Science 2020 18:10
    Content type: Research Published on:

  44. An amendment to this paper has been published and can be accessed via the original article.

    Authors: Ju Bai, Aili He, Chen Huang, Juan Yang, Wanggang Zhang, Jianli Wang, Yun Yang, Pengyu Zhang, Yang Zhang and Fuling Zhou
    Citation: Proteome Science 2020 18:9
    Content type: Correction Published on:

    The original article was published in Proteome Science 2014 12:49

  45. Within the complex wheat flour proteome, the gluten proteins have attracted most of the attention because of their importance in determining the functional properties of wheat flour doughs and their roles in h...

    Authors: Susan B. Altenbach, Han-Chang Chang and Annamaria Simon-Buss
    Citation: Proteome Science 2020 18:8
    Content type: Research Published on:

  46. Cerebral microdialysis (CMD) is a minimally invasive technique for sampling the interstitial fluid in human brain tissue. CMD allows monitoring the metabolic state of tissue, as well as sampling macromolecules...

    Authors: Lovisa Tobieson, Zita Czifra, Karin Wåhlén, Niklas Marklund and Bijar Ghafouri
    Citation: Proteome Science 2020 18:7
    Content type: Research Published on:

  47. Protein arginine methylation reaction is catalyzed by protein arginine methyltransferase (PRMT) and the modification is implicated in various diseases including cancer. Currently, thousands of arginine methyla...

    Authors: Yongchul Lim, Ju Yeon Lee, Su Jin Ha, Suyeun Yu, Jung Kyong Shin and Hee Cheol Kim
    Citation: Proteome Science 2020 18:6
    Content type: Research Published on:

  48. Marine medaka is among the most popular models of fish species for ecotoxicology and environmental research and proteomic studies are useful tools for understanding the molecular responses of medaka upon expos...

    Authors: Celia Sze-Nga Kwok, Kaze King-Yip Lai, Sai-Wo Lam, Kin-Ka Chan, Steven Jing-Liang Xu and Fred Wang-Fat Lee
    Citation: Proteome Science 2020 18:5
    Content type: Research Published on:

  49. Members of the family of NEK protein kinases (NIMA-related kinases) were described to have crucial roles in regulating different aspects of the cell cycle. NEK10 was reported to take part in the maintenance of...

    Authors: Andressa Peres de Oliveira, Fernanda Luisa Basei, Priscila Ferreira Slepicka, Camila de Castro Ferezin, Talita D. Melo-Hanchuk, Edmarcia Elisa de Souza, Tanes I. Lima, Valquiria Tiago dos Santos, Davi Mendes, Leonardo Reis Silveira, Carlos Frederico Martins Menck and Jörg Kobarg
    Citation: Proteome Science 2020 18:4
    Content type: Research Published on:

  50. It has been previously shown that doxycycline (Doxy) protects the kidney from preservation injury by inhibition of matrix metalloproteinase. However, the precise molecular mechanism involved in this protection...

    Authors: Michael A. J. Moser, Katherine Sawicka, Jolanta Sawicka, Aleksandra Franczak, Alejandro Cohen, Iwona Bil-Lula and Grzegorz Sawicki
    Citation: Proteome Science 2020 18:3
    Content type: Research Published on:
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