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  1. Transforming growth factor-beta (TGF-β) signal is an important pathway involved in all stages of liver hepatocellular carcinoma (LIHC) initiation and progression. Therefore, targeting TGF- β pathway may be a p...

    Authors: Jingsheng Liao, Qi Liu, Jingtang Chen, Zhibin Lu, Huiting Mo and Jun Jia
    Citation: Proteome Science 2022 20:11
    Content type: Research Published on:

  2. Acute respiratory distress syndrome (ARDS) is characterized by refractory hypoxemia caused by accumulation of pulmonary fluid, which is related to inflammatory cell infiltration, impaired tight junction of pul...

    Authors: Xu-Peng Wen, Guo Long, Yue-Zhong Zhang, He Huang, Tao-Hua Liu and Qi-Quan Wan
    Citation: Proteome Science 2022 20:10
    Content type: Research Published on:

  3. The epidermal growth factor receptor (EGFR) overexpression is found in metastatic colorectal cancer (mCRC). Targeted molecular therapies such as monoclonal antibodies (mAbs) and tyrosine kinase inhibitors (TKI...

    Authors: Thomanai Lamtha, Sucheewin Krobthong, Yodying Yingchutrakul, Pawitrabhorn Samutrtai, Christopher Gerner, Lueacha Tabtimmai and Kiattawee Choowongkomon
    Citation: Proteome Science 2022 20:9
    Content type: Research Published on:

  4. Bacterial meningitis (BM) is a life-threatening infectious disease of the central nervous system in infants and children. To date, no diagnostic methods for the early and precise diagnosis of paediatric BM hav...

    Authors: Ting Luo, Sai Yang, Yan Chen, Shulei Liu, Liming Yang, Nanfei Hu, Ye Ma, Jun Qiu, Kewei Wang, Liping Li and Lihong Tan
    Citation: Proteome Science 2022 20:8
    Content type: Research Published on:

  7. The surveillance and therapy of early-stage cancer would be better for patients’ prognosis. However, the extreme trace amount of tissue samples in different stages have limited in portraying the characterizati...

    Authors: Lingling Li, Hui Liu, Yan Li, Chunmei Guo, Bing Wang, Dan Shen, Qiao Zhang and Chen Ding
    Citation: Proteome Science 2022 20:5
    Content type: Research Published on:

  8. The pathogen of banana Fusarium oxysporum f. sp. cubense race 4(Foc4) infects almost all banana species, and it is the most destructive. The molecular mechanism of the interactions between Fusarium oxysporum and ...

    Authors: Hui Fang, Cheng Zhong and Chunyan Tang
    Citation: Proteome Science 2022 20:4
    Content type: Research Published on:

  9. B-cell acute lymphoblastic leukemia (B-ALL) is the most common malignancy of childhood. Even though significant progresses have been made in the treatment of B-ALL, some pediatric B-ALL have still poor prognos...

    Authors: Runhong Yu, Shiwei Yang, Yufeng Liu and Zunmin Zhu
    Citation: Proteome Science 2022 20:3
    Content type: Research Published on:

  10. The Australian Imaging and Biomarker Lifestyle (AIBL) study of aging is designed to aid the discovery of biomarkers. The current study aimed to discover differentially expressed plasma proteins that could yiel...

    Authors: Scott B. Laffoon, James D. Doecke, Anne M. Roberts, Jennifer A. Vance, Benjamin D. Reeves, Kelly K. Pertile, Rebecca L. Rumble, Chris J. Fowler, Brett Trounson, David Ames, Ralph Martins, Ashley I. Bush, Colin L. Masters, Paul A. Grieco, Edward A. Dratz and Blaine R. Roberts
    Citation: Proteome Science 2022 20:2
    Content type: Research Published on:

  11. Cardiovascular diseases remain the leading cause of morbidity and mortality worldwide, most of which are caused by atherosclerosis. Discerning processes that participate in macrophage-to-foam cell formation ar...

    Authors: Yali Zhang, Yu Fu, Linying Jia, Chenyang Zhang, Wenbin Cao, Naqash Alam, Rong Wang, Weirong Wang, Liang Bai, Sihai Zhao and Enqi Liu
    Citation: Proteome Science 2022 20:1
    Content type: Research Published on:

  12. Streptococcus agalactiae is a common colonizer of the rectovaginal tract and lead to infectious diseases of neonatal and non-pregnant adults, which also causes infectious disease in fish and a zoonotic risk as w...

    Authors: Xinjin Chen, Bolin Fan, Chenlong Fan, Zhongliang Wang, Eakapol Wangkahart, Yucong Huang, Yu Huang, Jichang Jian and Bei Wang
    Citation: Proteome Science 2021 19:14
    Content type: Research Published on:

  14. Gout is a common and complex form of immunoreactive arthritis based on hyperuricemia, while the symptoms would turn to remission or even got worse. So, it is hard to early identify whether an asymptomatic hype...

    Authors: Guangqi Chen, Jiafen Cheng, Hanjie Yu, Xiao Huang, Hui Bao, Ling Qin, Ling Wang, Yaxiang Song, Xinying Liu and Ai Peng
    Citation: Proteome Science 2021 19:12
    Content type: Research Published on:

  15. The target-decoy strategy effectively estimates the false-discovery rate (FDR) by creating a decoy database with a size identical to that of the target database. Decoy databases are created by various methods,...

    Authors: Sangjeong Lee, Heejin Park and Hyunwoo Kim
    Citation: Proteome Science 2021 19:11
    Content type: Research Published on:

  17. Tibetan pigs (TP) exhibit heritable adaptations to their hypoxic environments as a result of natural selection. However, candidate proteins that affect the sperm quality of boars on plateaus have not yet been ...

    Authors: Yanling Zhao, Yaomei Wang, Feipeng Guo, Bo Lu, Jiale Sun, Jianzhou Wang and Zili Ren
    Citation: Proteome Science 2021 19:9
    Content type: Research Published on:

  18. Kiwifruit (Actinidia chinensis var. Chinensis) is abundant with vitamin C and is a rapidly developing crop in China, New Zealand, and other countries. It has been widely used as a raw material for food and kiwifr...

    Authors: Yu Zhang, Yuexing Wang, Wanying Zhou, Shimao Zheng and Wenhui Zhang
    Citation: Proteome Science 2021 19:8
    Content type: Research Published on:

  19. The black soldier fly (Hermetia illucens) has significant economic potential. The larvae can be used in financially viable waste management systems, as they are voracious feeders able to efficiently convert low-q...

    Authors: Yu-Bo Lin, Jing-Jing Rong, Xun-Fan Wei, Zhuo-Xiao Sui, Jinhua Xiao and Da-Wei Huang
    Citation: Proteome Science 2021 19:7
    Content type: Research Published on:

  20. Spotted stem borer- Chilo partellus - a Lepidopteran insect pest of Sorghum bicolor is responsible for major economic losses. It is an oligophagous pest, which bores through the plant stem, causing ‘deadheart’ an...

    Authors: Vaijayanti A. Tamhane, Surhud S. Sant, Abhilash R. Jadhav, Abdul R. War, Hari C. Sharma, Abdul Jaleel and Akanksha S. Kashikar
    Citation: Proteome Science 2021 19:6
    Content type: Research Published on:

  22. Escherichia coli (E. coli) is the principal pathogen that causes biofilm formation. Biofilms are associated with infectious diseases and antibiotic resistance. This study employed proteomic analysis to identify d...

    Authors: Huiyi Song, Ni Lou, Jianjun Liu, Hong Xiang and Dong Shang
    Citation: Proteome Science 2021 19:4
    Content type: Research Published on:

  23. Preterm birth (PTB) is one of major causes of perinatal mortality and neonatal morbidity, but knowledge of its complex etiology is still limited. Here we present cervicovaginal fluid (CVF) protein profiles of ...

    Authors: Young Eun Kim, Kwonseong Kim, Han Bin Oh, Sung Ki Lee and Dukjin Kang
    Citation: Proteome Science 2021 19:3
    Content type: Research Published on:

  24. Apple replant disease (ARD) has been reported from all major fruit-growing regions of the world, and is often caused by biotic factors (pathogen fungi) and abiotic factors (phenolic compounds). In order to cla...

    Authors: Rong Zhang, Weitao Jiang, Xin Liu, Yanan Duan, Li Xiang, Yanfang Wang, Yuanmao Jiang, Xiang Shen, Xuesen Chen, Chengmiao Yin and Zhiquan Mao
    Citation: Proteome Science 2021 19:2
    Content type: Research Published on:

  25. Protein lysine malonylation, a novel post-translational modification (PTM), has been recently linked with energy metabolism in bacteria. Staphylococcus aureus is the third most important foodborne pathogen worldw...

    Authors: Yanan Shi, Jingjing Zhu, Yan Xu, Xiaozhao Tang, Zushun Yang and Aixiang Huang
    Citation: Proteome Science 2021 19:1
    Content type: Research Published on:

  26. Stemazole is a novel small molecule that has been suggested to have the ability to protect multiple stem cells. The proliferation-promoting activity and promising neuroprotective effects of stemazole make it a...

    Authors: Huajun Li, Yubo Zhang, Jing Zhang, Chaoran Zhao, Yizi Zhu and Mei Han
    Citation: Proteome Science 2020 18:12
    Content type: Research Published on:

  28. Tuberculosis (TB) is one of the world’s most problematic infectious diseases. The pathogen Mycobacterium tuberculosis (Mtb) is contained by the immune system in people with latent TB infection (LTBI). No overt di...

    Authors: Takele Teklu, Biniam Wondale, Biruhalem Taye, Milkessa Hailemariam, Shiferaw Bekele, Mesfin Tamirat, Aboma Zewude, Temesgen Mohamed, Girmay Medhin, Mengistu Legesse, Yanbao Yu, Gobena Ameni and Rembert Pieper
    Citation: Proteome Science 2020 18:10
    Content type: Research Published on:

  29. An amendment to this paper has been published and can be accessed via the original article.

    Authors: Ju Bai, Aili He, Chen Huang, Juan Yang, Wanggang Zhang, Jianli Wang, Yun Yang, Pengyu Zhang, Yang Zhang and Fuling Zhou
    Citation: Proteome Science 2020 18:9
    Content type: Correction Published on:

    The original article was published in Proteome Science 2014 12:49

  30. Within the complex wheat flour proteome, the gluten proteins have attracted most of the attention because of their importance in determining the functional properties of wheat flour doughs and their roles in h...

    Authors: Susan B. Altenbach, Han-Chang Chang and Annamaria Simon-Buss
    Citation: Proteome Science 2020 18:8
    Content type: Research Published on:

  31. Cerebral microdialysis (CMD) is a minimally invasive technique for sampling the interstitial fluid in human brain tissue. CMD allows monitoring the metabolic state of tissue, as well as sampling macromolecules...

    Authors: Lovisa Tobieson, Zita Czifra, Karin Wåhlén, Niklas Marklund and Bijar Ghafouri
    Citation: Proteome Science 2020 18:7
    Content type: Research Published on:

  32. Protein arginine methylation reaction is catalyzed by protein arginine methyltransferase (PRMT) and the modification is implicated in various diseases including cancer. Currently, thousands of arginine methyla...

    Authors: Yongchul Lim, Ju Yeon Lee, Su Jin Ha, Suyeun Yu, Jung Kyong Shin and Hee Cheol Kim
    Citation: Proteome Science 2020 18:6
    Content type: Research Published on:

  33. Marine medaka is among the most popular models of fish species for ecotoxicology and environmental research and proteomic studies are useful tools for understanding the molecular responses of medaka upon expos...

    Authors: Celia Sze-Nga Kwok, Kaze King-Yip Lai, Sai-Wo Lam, Kin-Ka Chan, Steven Jing-Liang Xu and Fred Wang-Fat Lee
    Citation: Proteome Science 2020 18:5
    Content type: Research Published on:

  34. Members of the family of NEK protein kinases (NIMA-related kinases) were described to have crucial roles in regulating different aspects of the cell cycle. NEK10 was reported to take part in the maintenance of...

    Authors: Andressa Peres de Oliveira, Fernanda Luisa Basei, Priscila Ferreira Slepicka, Camila de Castro Ferezin, Talita D. Melo-Hanchuk, Edmarcia Elisa de Souza, Tanes I. Lima, Valquiria Tiago dos Santos, Davi Mendes, Leonardo Reis Silveira, Carlos Frederico Martins Menck and Jörg Kobarg
    Citation: Proteome Science 2020 18:4
    Content type: Research Published on:

  35. It has been previously shown that doxycycline (Doxy) protects the kidney from preservation injury by inhibition of matrix metalloproteinase. However, the precise molecular mechanism involved in this protection...

    Authors: Michael A. J. Moser, Katherine Sawicka, Jolanta Sawicka, Aleksandra Franczak, Alejandro Cohen, Iwona Bil-Lula and Grzegorz Sawicki
    Citation: Proteome Science 2020 18:3
    Content type: Research Published on:

  36. Traditional studies of the cardiac proteome have mainly investigated in an animal model by two-dimensional gel electrophoresis (2-DE). However, the results have not been of satisfactory quality for an understa...

    Authors: Sun Ha Lim, Jongwon Lee and Mee-Jung Han
    Citation: Proteome Science 2020 18:2
    Content type: Research Published on:

  37. Irritable bowel syndrome (IBS) has been gradually recognized as a disorder of the brain-gut interaction, but the molecular changes in the brain and colon that occur in disease development remain poorly underst...

    Authors: Beihua Zhang, Hong Xue, Wei Wang, Ting Chen, Min Su, Nan Kang, Jianqin Yang, Zhaoxiang Bian, Fengyun Wang and Xudong Tang
    Citation: Proteome Science 2020 18:1
    Content type: Research Published on:

  39. Chronic Kidney Disease (CKD) is a global health problem annually affecting millions of people around the world. It is a comprehensive syndrome, and various factors may contribute to its occurrence. In this stu...

    Authors: Amir Taherkhani, Reyhaneh Farrokhi Yekta, Maede Mohseni, Massoud Saidijam and Afsaneh Arefi Oskouie
    Citation: Proteome Science 2019 17:7
    Content type: Review Published on:

  40. Polypterus senegalus can fully regenerate its pectoral lobed fins, including a complex endoskeleton, with remarkable precision. However, despite the enormous potential of this species for use in medical research,...

    Authors: Suxiang Lu, Qian Xiong, Kang Du, Xiaoni Gan, Xuzhen Wang, Liandong Yang, Ying Wang, Feng Ge and Shunping He
    Citation: Proteome Science 2019 17:6
    Content type: Research Published on:

  42. In previous study, we performed next-gene sequencing to investigate the differentially expressed transcripts of bovine follicular granulosa cells (GCs) at dominant follicle (DF) and subordinate follicle (SF) s...

    Authors: Shuning Hou, Qingling Hao, Zhiwei Zhu, Dongmei Xu, Wenzhong Liu, Lihua Lyu and Pengfei Li
    Citation: Proteome Science 2019 17:4
    Content type: Research Published on:

  43. The periodontal ligament is essential for homeostasis of periodontal tissue. A hypoxic milieu of the periodontal tissue is generated under periodontitis or during orthodontic treatment, which affects the perio...

    Authors: Qiwen Li, Tao Luo, Wenxin Lu, Xiaoxiao Yi, Zhihe Zhao and Jun Liu
    Citation: Proteome Science 2019 17:3
    Content type: Research Published on:

  44. The rumen microbiota is one of the most complex consortia of anaerobes, involving archaea, bacteria, protozoa, fungi and phages. They are very effective at utilizing plant polysaccharides, especially cellulose...

    Authors: Hana Sechovcová, Lucie Kulhavá, Kateřina Fliegerová, Mária Trundová, Daniel Morais, Jakub Mrázek and Jan Kopečný
    Citation: Proteome Science 2019 17:2
    Content type: Research Published on:

  45. Non-alcoholic fatty liver disease (NAFLD) is caused by excessive accumulation of fat within the liver, leading to further severe conditions such as non-alcoholic steatohepatitis (NASH). Progression of healthy ...

    Authors: Peerut Chienwichai, Onrapak Reamtong, Usa Boonyuen, Trairak Pisitkun, Poorichaya Somparn, Prapin Tharnpoophasiam, Suwalee Worakhunpiset and Supachai Topanurak
    Citation: Proteome Science 2019 17:1
    Content type: Research Published on:

  46. Abiotic stress reduces photosynthetic yield and plant growth, negatively impacting global crop production and is a major constraint faced by agriculture. However, the knowledge on the impact on plants under ex...

    Authors: Débora Parrine, Bo-Sen Wu, Bilal Muhammad, Keith Rivera, Darryl Pappin, Xin Zhao and Mark Lefsrud
    Citation: Proteome Science 2018 16:20
    Content type: Research Published on:

  47. Maize seedlings are constantly exposed to inorganic phosphate (Pi)-limited environments. To understand how maize cope with low Pi (LP) and high Pi (HP) conditions, physiological and global proteomic analysis o...

    Authors: Yanling Sun, Chunhua Mu and Xia Liu
    Citation: Proteome Science 2018 16:19
    Content type: Research Published on:

  48. Calcitonin gene-related peptide (CGRP) contributes to bone formation by stimulating bone marrow stromal cell (BMSC) proliferation and differentiation. However, the proliferative and apoptotic effects of CGRP o...

    Authors: Jianqun Wu, Song Liu, Zhao Wang, Shenghui Ma, Huan Meng and Jijie Hu
    Citation: Proteome Science 2018 16:18
    Content type: Research Published on:

  50. The non-receptor tyrosine kinase, SRMS (Src-related kinase lacking C-terminal regulatory tyrosine and N-terminal myristoylation sites) is a member of the BRK family kinases (BFKs) which represents an evolution...

    Authors: Raghuveera Kumar Goel, Mona Meyer, Marta Paczkowska, Jüri Reimand, Frederick Vizeacoumar, Franco Vizeacoumar, TuKiet T. Lam and Kiven Erique Lukong
    Citation: Proteome Science 2018 16:16
    Content type: Research Published on:
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