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Figure 3 | Proteome Science

Figure 3

From: Potential plasma biomarkers for progression of knee osteoarthritis using glycoproteomic analysis coupled with a 2D-LC-MALDI system

Figure 3

Expression of candidate biomarkers in synovial tissues collected from OA knee joints. (A) Results of in situ hybridization for clusterin, hemopexin, MSP, and AGP-2 mRNA in OA synovial tissue. Clusterin, hemopexin, and MSP expression were observed primarily in synovial lining cells (thick arrows), while the expression of AGP-2 was mostly observed in endothelial cells (arrowheads). Expression of hemopexin was also observed in endothelial cells (arrowheads) and fibroblast-like cells (thin arrows). Bars, 50 μm. (B) Results of western blotting analysis of synovial tissue lysates. Clusterin and hemopexin were confirmed in all samples. Numbers above the lanes indicate numbers of synovium samples. PC: positive control.

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