Table 7 Other proteins with known functions that had significantly altered expression in newborn rats compared to E15.5 fetuses changed proteins (P < 0.05)
From: A comparison of E15.5 fetus and newborn rat serum proteomes
Protein name | Protein ID | T-value | Increasing (↑) / Decreasing (↓) | Functions (noted in uniprot database) |
|---|---|---|---|---|
Isoform 1 of Serotransferrin | IPI00679202 | 57.1 | ↑ | iron binding transport |
Zdhhc5 Uncharacterized protein | IPI00193933 | 22.9 | ↑ | contains 1 DHHC-type zinc finger |
CD320 antigen-like | IPI00365976 | 6.2 | ↑ | augmenting the proliferation of PC precursors generated by IL-10 |
Afamin | IPI00207668 | 5.5 | ↑ | vitamin E binding protein |
hypothetical protein | IPI00781081 | 3.9 | ↑ | binding various heavy metals |
Myoblast determination protein 1 | IPI00205974 | 3.7 | ↑ | myogenic factor |
Gc Vitamin D-binding protein | IPI00194097 | 3.2 | ↑ | carrying the vitamin D sterols, preventing polymerization of actin |
Heat shock protein HSP 90-beta | IPI00471584 | −3.4 | ↓ | molecular chaperone in cell cycle control and signal transduction |
Fga protein | IPI00202651 | −3.4 | ↓ | yielding monomers, acting as a cofactor in platelet aggregation |
Ywhaz 14-3-3 protein zeta\delta | IPI00324893 | −4 | ↓ | adapter protein in the regulation of signaling pathways |
actin | IPI00189819 | −4.3 | ↓ | involved in cell motility |
Collagen alpha-1(III) chain | IPI00366944 | −5.3 | ↓ | soft connective tissues along with type I collagen |
Collagen alpha-2(I) chain | IPI00188921 | −5.9 | ↓ | member of group I collagen |
Col1a1 Rat alpha-1 type I collagen | IPI00188909 | −6 | ↓ | member of group I collagen |
Scn5a 228 kDa protein | IPI00231550 | −6.7 | ↓ | mediating the voltage-dependent sodium ion permeability |
Platelet factor 4 | IPI00206634 | −7.6 | ↓ | chemotactic for neutrophils and monocytes, Inhibits endothelial cell proliferation |
heat shock cognate 71 kDa protein-like | IPI00207355 | −7.7 | ↓ | cooperation with other chaperones |
Cadherin-5 | IPI00768626 | −9.8 | ↓ | calcium dependent cell adhesion proteins |
Isoform Gamma-A of Fibrinogen | IPI00190759 | −10 | ↓ | yielding monomers, acting as a cofactor in platelet aggregation |
growth factor-binding protein 4 | IPI00206239 | −11.9 | ↓ | alter the interaction of IGFs with their cell surface receptors |