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Table 1 Significantly up-regulated proteins in the CD133 + Huh7 cells

From: Label-free quantitative proteomics of CD133-positive liver cancer stem cells

Accession Protein description Score Unique peptides Hepatocyte area CD133 - Huh7 area CD133 + Huh7 area IDEAL-Q CD133 + /CD133 - IDEAL-Q CD133 + /Hepatocyte P-value a MaxQuant CD133 + /CD133 -b Plasma membrane c
IPI00216138 Transgelin 552 10 0.21 ± 0.05 0.13 ± 0.06 2.11 ± 0.30 15.96 9.99 <0.001 33.94  
IPI00012540 Prominin-1 (CD133) 170 4 0.01 ± 0.01 0.05 ± 0.01 0.69 ± 0.09 15.24 76.22 <0.001 124.06 O
IPI00418471 Vimentin 1726 30 0.38 ± 0.03 0.82 ± 0.06 6.77 ± 0.47 8.24 17.77 <0.001 21.51 O
IPI00218918 Annexin A1 303 5 0.02 ± 0.002 0.04 ± 0.01 0.33 ± 0.03 7.83 21.93 <0.001 101.44 O
IPI00186460 Collagen alpha-1(II) chain 227 4 0.01 ± 0.01 0.15 ± 0.05 0.94 ± 0.06 6.10 67.07 <0.001 11.95  
IPI00024095 Annexin A3 919 15 0.15 ± 0.003 0.44 ± 0.07 2.69 ± 0.48 6.10 17.70 <0.001 17.13 O
IPI00329650 Nucleoporin NUP53 252 4 0.05 ± 0.02 0.28 ± 0.04 1.29 ± 0.13 4.71 26.41 <0.001 3.62 O
IPI00296215 Tumor-associated calcium signal transducer 1 (EpCAM) 204 3 0.01 ± 0.004 0.12 ± 0.01 0.31 ± 0.02 2.56 27.73 0.010 6.17 O
IPI00386208 Gastric-associated differentially-expressed protein YA61P 224 4 0.01 ± 0.01 0.42 ± 0.04 0.97 ± 0.07 2.34 108.22 0.008 13.90  
IPI00022977 Creatine kinase B-type 1181 19 0.86 ± 0.15 6.39 ± 0.58 13.50 ± 2.43 2.11 15.66 0.009 2.03  
  1. a Significance B based on log(2) transformed ratios and intensity between CD133+ Huh7 cells and CD133- Huh7 cells.
  2. b The ratio was calculated by MaxQuant label-free quantification.
  3. c Proteins possibly locate on plasma membrane from Gene Ontology Cellular Component (GOCC) database.