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Table 3 Selected probability marginals for the cell cycle pathway (6 datasets + Buffa)

From: Identifying transcription factors and microRNAs as key regulators of pathways using Bayesian inference on known pathway structures

Node

Marginals

  

Scenario #1

  

Scenario #2

 
 

very low

medium low

medium

medium high

very high

very low

medium low

medium

medium high

very high

SMAD3

0.29

0.39

0.18

0.09

0.06

0.21

0.31

0.19

0.12

0.16

CDKN2B

0.99

 

0.01

 

0.01

0.48

0.11

0.12

0.14

0.14

CCND1

  

(de)*

  

(de)

    

CDK4

0.01

 

0.01

0.82

0.16

0.12

0.2

0.18

0.28

0.22

TFE3

  

0.69

0.31

  

0.04

0.31

0.65

0.01

LMO2

 

0.06

0.82

0.12

0.01

0.01

0.14

0.77

0.08

0

ELK4

0.98

0.01

 

0.01

 

0.98

 

0.01

 

0.01

SREBF2

0.01

 

0.99

  

0.09

0.01

0.89

0.01

 

PAX4

1.0

    

1.0

    

NFIC

0.22

0.36

0.35

0.07

 

0.14

0.36

0.29

0.19

0.01

STAT6

0.01

0.01

0.09

0.9

   

0.09

0.9

0.01

SREBF1

   

0.98

0.01

  

0.07

0.9

0.03

NFIB

0.12

0.26

0.32

0.23

0.08

0.13

0.29

0.29

0.21

0.07

PPARA

0.99

0.01

   

0.98

0.01

 

0.01

0.01

hsa-mir-375

0.04

0.1

0.11

0.33

0.42

0.04

0.07

0.15

0.33

0.42

  1. *de: the gene is differentially expressed and was used as evidence.