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Figure 4 | Proteome Science

Figure 4

From: Members of the high mobility group B protein family are dynamically expressed in embryonic neural stem cells

Figure 4

Embryonic HMGB2-/- neurospheres differentiate similarly to wt ones. Quantitative analysis of the distribution of HMGB2-/- neurosphere sizes (A) in E16.5 HMGB2-/- neurospheres compared to WT E16.5 neurospheres, (B) numbers of BrdU+ cells/sphere, (C) numbers of activated caspase 3+ cells/sphere. (D) BrdU+ labeled spheres from HMGB2-/- and WT E16.5 mice. (E, F) Differentiation of E16.5 HMGB2-/- neurospheres give rise to GFAP+, βIII tubulin+, and CNP+ cells. N=4 biological replicates for each genotype and 15 neurospheres/biological replicate. Scale bar: 20 μm. * indicates that p≤0.05.

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Proteome Science

ISSN: 1477-5956